[HTML][HTML] Sulforaphane: A broccoli bioactive phytocompound with cancer preventive potential
AE Kaiser, M Baniasadi, D Giansiracusa… - Cancers, 2021 - mdpi.com
There is substantial and promising evidence on the health benefits of consuming broccoli
and other cruciferous vegetables. The most important compound in broccoli, glucoraphanin …
and other cruciferous vegetables. The most important compound in broccoli, glucoraphanin …
New highlights on the health-improving effects of sulforaphane
A Briones-Herrera, D Eugenio-Pérez… - Food & function, 2018 - pubs.rsc.org
In this paper, we review recent evidence about the beneficial effects of sulforaphane (SFN),
which is the most studied member of isothiocyanates, on both in vivo and in vitro models of …
which is the most studied member of isothiocyanates, on both in vivo and in vitro models of …
Sulforaphane reactivates cellular antioxidant defense by inducing Nrf2/ARE/Prdx6 activity during aging and oxidative stress
E Kubo, B Chhunchha, P Singh, H Sasaki, DP Singh - Scientific reports, 2017 - nature.com
Upon oxidative stress and aging, Nrf2 (NFE2-related factor2) triggers antioxidant defense
genes to defends against homeostatic failure. Using human (h) or rat (r) lens epithelial cells …
genes to defends against homeostatic failure. Using human (h) or rat (r) lens epithelial cells …
Long noncoding RNAs and sulforaphane: a target for chemoprevention and suppression of prostate cancer
Long noncoding RNAs (lncRNAs) have emerged as important in cancer development and
progression. The impact of diet on lncRNA expression is largely unknown. Sulforaphane …
progression. The impact of diet on lncRNA expression is largely unknown. Sulforaphane …
Sulforaphane bioavailability and chemopreventive activity in men presenting for biopsy of the prostate gland: A randomized controlled trial
Previous studies suggest compounds such as sulforaphane (SFN) derived from cruciferous
vegetables may prevent prostate cancer development and progression. This study …
vegetables may prevent prostate cancer development and progression. This study …
Identification of novel NRF2-dependent genes as regulators of lead and arsenic toxicity in neural progenitor cells
Abstract Lead (Pb) and arsenic (As) are prevalent metal contaminants in the environment.
Exposures to these metals are associated with impaired neuronal functions and adverse …
Exposures to these metals are associated with impaired neuronal functions and adverse …
Sulforaphane and Sulforaphane‐Nitrile Metabolism in Humans Following Broccoli Sprout Consumption: Inter‐individual Variation, Association with Gut Microbiome …
Scope The glucosinolate glucoraphanin from broccoli is converted to sulforaphane (SFN) or
sulforaphane‐nitrile (SFN‐NIT) by plant enzymes or the gut microbiome. Human feeding …
sulforaphane‐nitrile (SFN‐NIT) by plant enzymes or the gut microbiome. Human feeding …
Sulforaphane-induced Klf9/Prdx6 axis acts as a molecular switch to control redox signaling and determines fate of cells
B Chhunchha, E Kubo, DP Singh - Cells, 2019 - mdpi.com
Sulforaphane (SFN), an activator of transcription factor Nrf2 (NFE2-related factor), modulates
antioxidant defense by Nrf2-mediated regulation of antioxidant genes like Peroxiredoxin 6 …
antioxidant defense by Nrf2-mediated regulation of antioxidant genes like Peroxiredoxin 6 …
Cruciferous vegetables as antioxidative, chemopreventive and antineoplasic functional foods: Preclinical and clinical evidences of sulforaphane against prostate …
PMP Ferreira, LARL Rodrigues… - Current …, 2018 - ingentaconnect.com
Background: Sulforaphane (SF, 1-isothiocyanato-4-(methyl-sulfinyl)-butane) is found in
broccoli, cabbage and cauliflower. Methods: we performed a critical review on the …
broccoli, cabbage and cauliflower. Methods: we performed a critical review on the …
A functional pseudogene, NMRAL2P, is regulated by Nrf2 and serves as a coactivator of NQO1 in sulforaphane‐treated colon cancer cells
Scope The anticancer agent sulforaphane (SFN) acts via multiple mechanisms to modulate
gene expression, including the induction of nuclear factor (erythroid‐derived 2)‐like 2 (Nrf2) …
gene expression, including the induction of nuclear factor (erythroid‐derived 2)‐like 2 (Nrf2) …