Oxygen is essential for living organisms. Molecular oxygen binds to hemoglobin and is
delivered to every organ in the body. In several cardiovascular diseases or anemia, local …

Simple Summary The regulation of hypoxia has recently emerged as having a central impact
in mitochondrial function and dysfunction in various diseases, including the major disorders …

Clinical use of doxorubicin (DOX) is limited because of its cardiotoxicity, referred to as DOX-
induced cardiomyopathy (DIC). Mitochondria-dependent ferroptosis, which is triggered by …

Summary Ischemia-reperfusion (I/R) injury is a promising therapeutic target to improve
clinical outcomes after acute myocardial infarction. Ferroptosis, triggered by iron overload …

Myocardial infarction (MI) is a major cause of mortality and disability globally. MI results from
acute or chronic myocardial ischemia characterized by an imbalance of oxygen demand and …

Doxorubicin (DOX) is an effective anti-cancer agent for various malignancies. Nevertheless,
it has a side effect of cardiotoxicity, referred to as doxorubicin-induced cardiomyopathy …

BACKGROUND: Cardiac autoantibodies (cAAbs) are involved in the progression of adverse
cardiac remodeling in heart failure (HF). However, our understanding of cAAbs in HF is …

Background: Dilated cardiomyopathy (DCM) is a life-threatening disease, resulting in
refractory heart failure. An immune disorder underlies the pathophysiology associated with …

Background Hypoxia is one of the important characteristics of synovial microenvironment in
rheumatoid arthritis (RA), and plays an important role in synovial hyperplasia. In terms of cell …

Myocardial hypoxia reperfusion (H/R) injury is the paradoxical exacerbation of myocardial
damage, caused by the sudden restoration of blood flow to hypoxia affected myocardium. It …