The testis is an important male reproductive organ, which ensures reproductive function via
the secretion of testosterone and the generation of spermatozoa. Testis development begins …

Spermatogenesis is a complex and dynamic process which is precisely controlledby genetic
and epigenetic factors. With the development of new technologies (eg, single-cell RNA …

Spermatogenesis is a multi-step biological process where mitotically active diploid (2n)
spermatogonia differentiate into haploid (n) spermatozoa via regulated meiotic …

Spermatogenesis is a complex process of germ cell division and differentiation that involves
extensive cross-talk between the developing germ cells and the somatic testicular cells …

Sertoli cells (Sc) are the sole target of follicle-stimulating hormone (FSH) in the testis and
attain functional maturation post-birth to significantly augment germ cell (Gc) division and …

A major change in the transcriptome of testicular Sertoli cells (Scs) at the onset of puberty
enables them to induce robust spermatogenesis. Through comprehensive literature mining …

Heat stress is a serious problem that affects animal husbandry by reducing growth and
reproductive performance of animals. Adding plant extracts to the diet is an effective way to …

In mammals, gonadal somatic cell lineage differentiation determines the development of the
bipotential gonad into either the ovary or testis. Sertoli cells, the only somatic cells in the …

TSPAN8 mediates signal transduction from extracellular cues and regulates cell
development, activation, growth, and motility. However, whether TSPAN8 is involved in the …

Tetraspanins, a superfamily of small integral membrane proteins, are characterized by four
transmembrane domains and conserved protein motifs that are configured into a unique …