Atherosclerotic diseases such as myocardial infarction, ischaemic stroke and peripheral
artery disease continue to be leading causes of death worldwide despite the success of …

The wide range of epithelial cell shapes reveals the complexity and diversity of the
intracellular mechanisms that serve to construct their morphology and regulate their …

In situ tissue engineering is an emerging field aiming at the generation of ready-to-use three-
dimensional tissues. One solution to supply a proper vascularization of larger tissues to …

Background: The optimal time for flap anastomosis to an arteriovenous loop remains
controversial. Whether perforator flaps and axially vascularized muscle or fasciocutaneous …

MicroRNAs are small noncoding RNAs that regulate gene expression at the
posttranscriptional level. Since many microRNAs have multiple mRNA targets, they are …

Angiogenesis is an integral part of the multiple myeloma (MM) microenvironment, and
affects tumorigenesis, progression, invasion, and metastasis. Exosomes are essential for …

Cardiovascular development is initiated soon after gastrulation as bilateral precardiac
mesoderm is progressively symmetrically determined at both sides of the developing …

Chronic wounds impose a significant healthcare burden to a broad patient population. Cell-
based therapies, while having shown benefits for the treatment of chronic wounds, have not …

Anti-citrullinated protein/peptide antibodies (ACPA) play important roles in the pathogenesis
of rheumatoid arthritis (RA). ACPA-positive (ACPA+) and ACPA-negative (ACPA−) RA were …

Formation of the vasculature is a critical step within the developing embryo and its disruption
causes early embryonic lethality. This complex process is driven by a cascade of signaling …