Epigenetics and genome stability

JX Feng, NC Riddle - Mammalian Genome, 2020 - Springer
Maintaining genome stability is essential to an organism's health and survival. Breakdown of
the mechanisms protecting the genome and the resulting genome instability are an …

Epigenetic landscape of HIV-1 infection in primary human macrophage

F Lu, U Zankharia, O Vladimirova, Y Yi… - Journal of …, 2022 - Am Soc Microbiol
Human immunodeficiency virus (HIV)-infected macrophages are long-lived cells that sustain
persistent virus expression, which is both a barrier to viral eradication and contributor to …

[HTML][HTML] Species-specific rewiring of definitive endoderm developmental gene activation via endogenous retroviruses through TET1-mediated demethylation

F Wu, Z Liufu, Y Liu, L Guo, J Wu, S Cao, Y Qin, N Guo… - Cell Reports, 2022 - cell.com
Transposable elements (TEs) are the major sources of lineage-specific genomic innovation
and comprise nearly half of the human genome, but most of their functions remain unclear …

Unified analysis of multiple ChIP-seq datasets

G Ma, IA Babarinde, Q Zhuang, AP Hutchins - DNA Modifications: Methods …, 2021 - Springer
High-throughput sequencing technologies are increasingly used in molecular cell biology to
assess genome-wide chromatin dynamics of proteins bound to DNA, through techniques …

CRISPR-mediated activation of transposable elements in embryonic stem cells

A Sakashita, M Ariura, SH Namekawa - piRNA: Methods and Protocols, 2022 - Springer
Mounting evidence has established that subsets of transposable elements (TEs) function as
gene regulatory elements in a cell type-and species-specific manner. Here we describe an …