Lectins are widely distributed proteins having ability of binding selectively and reversibly
with carbohydrates moieties and glycoconjugates. Although lectins have been reported from …

To date, a number of mannose-binding lectins have been isolated and characterized from
plants and fungi. These proteins are composed of different structural scaffold structures …

Lectins are a widely studied group of proteins capable of specific and reversible binding to
carbohydrates. Undoubtedly, the best characterized are those extracted from plants of the …

Fast and reliable evaluation of the hydrogen bond potential energy has a significant impact
in the drug design and development since it allows the assessment of large databases of …

Homology modeling is a computational approach to generate three-dimensional structures
of protein targets when experimental data about similar proteins are available. Although …

This study investigated and compared vascular actions of leguminous lectins obtained from
the Canavalia genus (Canavalia brasiliensis, Canavalia gladiata, and Canavalia maritima) …

Van der Waals forces are determinants of the formation of protein-ligand complexes.
Physical models based on the Lennard-Jones potential can estimate van der Waals …

A lectin from Canavalia virosa, Diocleinae subtribe, was purified by affinity chromatography
with Sephadex G-50 matrix and named ConV. The primary structure of ConV was obtained …

Diocleinae lectins are highly homologous in their primary structure which features metal
binding sites and a carbohydrate recognition domain (CRD). Differences in the biological …