Amides are a class of easily available compounds, and widely serve as versatile
intermediates in organic synthesis and medicinal chemistry. Amide-based transformations …

Conspectus Native to the Asia-Pacific region and widely applied in traditional Chinese
medicine, the genus Daphniphyllum has produced over 330 known Daphniphyllum …

The macrodaphniphyllamine-type, calyciphylline A-type, daphnilongeranin A-type, and
daphnicyclidin D-type alkaloids are four structurally related classes of Daphniphyllum …

The first enantioselective synthesis of (−)-himalensine A has been achieved in 22 steps. The
synthesis was enabled by a novel catalytic, enantioselective prototropic shift/furan Diels …

Among the famous Daphniphyllum alkaloids family, the calyciphylline A-type subfamily has
triggered particular interest from the organic synthesis community in recent years. Here, we …

The first total synthesis of (±)-and (−)-daphnillonin B, a daphnicyclidin-type alkaloid with a
new [7-6-5-7-5-5] A/B/C/D/E/F hexacyclic core, has been achieved. The [6-5-7] B/C/D ring …

Herein, we describe the convergent enantioselective total synthesis of himalensine A in 18
steps, enabled by a highly enantio-and diastereoselective construction of the morphan core …

We report the total syntheses of daphenylline (1), daphnipaxianine A (5), and himalenine D
(6), three Daphniphyllum alkaloids from the calyciphylline A subfamily. A pentacyclic …

The first total synthesis of daphgraciline has been achieved, which also represents the first
example of the synthesis of Daphniphyllum yuzurine-type alkaloids (∼ 50 members). The …

Daphnezomines A and B are structurally unusual Daphniphyllum alkaloids that contain a
unique aza-adamantane core skeleton. Herein, a modular approach to these alkaloids is …