4004 ESC Guidelines label use of medication should be limited to situations where it is in
the patient's interest to do so, with regard to the quality, safety, and efficacy of care, and only …

Purpose Genetic testing has advanced significantly since the publication of the 2011
HRS/EHRA Expert Consensus Statement on the State of Genetic Testing for the …

Sudden cardiac death and ventricular arrhythmias are a global health issue. Recently, a
new guideline for the management of ventricular arrhythmias and prevention of sudden …

Background and purpose Patients with neuromuscular conditions are at increased risk of
suffering perioperative complications related to anaesthesia. There is currently little specific …

In this final of a 5-part Focus Seminar series on precision medicine, we focus on
catecholaminergic polymorphic ventricular tachycardia (CPVT). This focus on CPVT allows …

Purpose of review This article aims to review the current and upcoming treatment options of
primary muscle channelopathies including the non-dystrophic myotonias and periodic …

Andersen-Tawil syndrome (ATS) is a rare inheritable disease associated with loss-of-
function mutations in KCNJ2, the gene coding the strong inward rectifier potassium channel …

Importance Patients with catecholaminergic polymorphic ventricular tachycardia (CPVT)
may experience life-threatening arrhythmic events (LTAEs) despite β-blocker treatment …

There have been remarkable advances in our knowledge of the underlying heritability of
cardiac arrhythmias. Long QT syndrome, Brugada syndrome, catecholaminergic …

Sudden death is a rare event in the pediatric population but with a social shock due to its
presentation as the first symptom in previously healthy children. Comprehensive autopsy in …