The incidence of ampulla of Vater carcinoma, a type of periampullary cancer, has been
increasing at an annual percentage rate of 0.9%. However, patients with ampulla of Vater …

Simple Summary Ampullary tumors are rare malignancies of the upper gastrointestinal tract.
Histologic, immunohistochemical and, most recently, genomic biomarkers have been used …

Purpose: Intrahepatic cholangiocarcinoma (IHC) is a heterogeneous tumor. The hidden-
genome classifier, a supervised machine learning–based algorithm, was used to quantify …

Importance Ampullary adenocarcinoma (AA) is characterized by clinical and genomic
heterogeneity. A previously developed genomic classifier defined biologically distinct …

Objective The aim of this study was to predict the long-term survival probability of patients
with ampullary adenocarcinoma (AAC), which would provide a theoretical basis for the long …

Ampullary adenocarcinoma is a rare malignancy that lacks standard systemic treatment. We
describe a case of recurrent metastatic ampullary adenocarcinoma of the pancreaticobiliary …

Ampullary cancers refer to tumors originating from the ampulla of Vater (the ampulla, the
intraduodenal portion of the bile duct, and the intraduodenal portion of the pancreatic duct) …

Mixed-type ampullary carcinoma is a subtype that combines intestinal-type (I-type) and
pancreatobiliary-type (PB-type) lesions, but few studies have examined its clinicopathologic …

BACKGROUND Ampullary cancer is a relatively rare malignant tumor in the digestive
system. Its incidence has increased in recent years. As for now, its biological characteristics …

Inferring the cancer-type specificities of ultra-rare, genome-wide somatic mutations is an
open problem. Traditional statistical methods cannot handle such data due to their ultra-high …