Neuropsychiatric disorders are multifactorial disorders with diverse aetiological factors.
Identifying treatment targets is challenging because the diseases are resulting from …

Perinatal brain injuries, including encephalopathy related to fetal growth restriction,
encephalopathy of prematurity, neonatal encephalopathy of the term neonate, and neonatal …

Over the last few years, awareness of autism spectrum disorder (ASD) in adults has
increased. The precise etiology of ASD is still unresolved. Animal research, genetic and …

Although aging itself is not a disease, there are many comorbidities that become more
common with aging. Heart disease, cancer, and other chronic illnesses are either more …

Perinatal insults are a leading cause of infant mortality and amongst survivors are frequently
associated with neurocognitive impairment, cerebral palsy (CP), and seizure disorders. The …

Spastic cerebral palsy (CP), despite the name, is not consistently identifiable by specific
brain lesions. CP animal models focus on risk factors for development of CP, yet few …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects 36 million
people worldwide, but currently has no effective treatment options. One of the original …

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system
(CNS). There is increasing evidence that MS is not only characterized by immune mediated …

Microglia of the developing brain have unique functional properties but how their activation
states are regulated is poorly understood. Inflammatory activation of microglia in the still …

Glutamate is an excitatory neurotransmitter of the central nervous system, which has a
central role in a complex communication network established between neurons, astrocytes …