Cancer immunotherapy, mainly including immune checkpoints-targeted therapy and the
adoptive transfer of engineered immune cells, has revolutionized the oncology landscape as …

Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease of the central nervous
system characterized by perivascular inflammation and demyelination and loss of …

Introduction The incidence rate of MS is a valuable indicator of the recent changes in the risk
of this disease, and it is widely implicated for health planning purposes. Objectives This …

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central
nervous system (CNS) characterized by inflammation, demyelination, axonal loss, and …

Overexpression of CD24 has a negative impact on breast cancer prognosis. We have
recently reported that the CD24 codon 57 Val/Val genotype (rs52812045) is associated with …

Overexpression of CD24 is an independent prognostic factor for breast cancer. Recently,
two polymorphisms in the CD24 gene were linked to disease risk and progression in …

A large number of risk alleles have been identified for multiple sclerosis (MS). However, how
genetic variations may affect pathogenesis remains largely unknown for most risk alleles …

Multiple sclerosis (MS) is one of the most common diseases of the central nervous system
(CNS) in the Iranian population. To date, association of many genes with the prevalence and …

CD24 binds to and suppresses inflammation triggered by danger-associated molecular
patterns such as heat shock proteins (HSPs) and high-mobility group box 1. Paradoxically …

Selectins are a family of adhesion receptors that bind to highly glycosylated molecules
expressed on the surface of leukocytes and endothelial cells. The interactions between …