Bronchiolitis obliterans syndrome (BOS) may develop after either lung or haematopoietic
stem cell transplantation (HSCT), with similarities in histopathological features and clinical …

Bronchiolitis obliterans syndrome (BOS) is the most common form of CLAD and is
characterized by airflow limitation and an obstructive spirometric pattern without high …

Chronic lung allograft dysfunction (CLAD) is a syndrome of progressive lung function
decline after lung transplant largely attributed to chronic rejection that can manifest with …

Background. Donor-derived cell-free DNA (dd-cfDNA) is a useful biomarker for the diagnosis
of acute allograft injury within the first 1 to 2 y after lung transplant, but its utility for …

Background: The immune mechanisms occurring during acute rejection (AR) and chronic
lung allograft dysfunction are a challenge for research and the balance between effector and …

Outcomes after lung transplantation (LTx) remain poor, despite advances in sequencing
technology and development of algorithms defining immunologic compatibility. Presently …

Background. Everolimus-based quadruple low calcineurin inhibitor (CNI) maintenance
immunosuppression has been shown to be effective in preserving short-term renal function …

Long‐term outcomes after lung transplantation remain inferior to those of other solid organ
groups. The significance of eosinophils detected on transbronchial biopsies (TBBx) after …

Background. Currently, the assessment of immunological risk in lung transplantation (LTx)
does not completely consider HLA compatibility at the molecular level. We have previously …

Introduction Chronic lung allograft dysfunction (CLAD) can take two forms: bronchiolitis
obliterans syndrome (BOS) or restrictive allograft syndrome (RAS). The aim was to …