Enzymatic asymmetric synthesis of the silodosin amine intermediate
RC Simon, JH Sattler, JE Farnberger, CS Fuchs… - Tetrahedron …, 2014 - Elsevier
Various enantiocomplementary ω-transaminases (ωTAs) were investigated in kinetic
resolution and asymmetric reductive amination reactions to prepare silodosin amine. Whilst …
resolution and asymmetric reductive amination reactions to prepare silodosin amine. Whilst …
Enantioselective synthesis of (−)-(R) Silodosin by ultrasound-assisted diastereomeric crystallization
IJ Barve, LH Chen, PCP Wei, JT Hung, CM Sun - Tetrahedron, 2013 - Elsevier
Enantioselective synthesis of clinically approved drug—Silodosin for the treatment of benign
prostatic hyperplasia from the commercially available compounds 1-acetyl-5-(2 …
prostatic hyperplasia from the commercially available compounds 1-acetyl-5-(2 …
Synthesis of Silodosin by Copper‐Catalysed C–C Arylation
F Calogero, P Allegrini, E Attolino… - European Journal of …, 2015 - Wiley Online Library
The synthesis of silodosin, an antidysuria drug, has been accomplished starting from
commercially available indoline. The synthetic strategy is based on CuI‐catalysed C–C …
commercially available indoline. The synthetic strategy is based on CuI‐catalysed C–C …
Method for producing indoline compound
T Motoyama, K Takata, Y Fukuhara, M Uemura… - US Patent …, 2018 - Google Patents
US9932308B2 - Method for producing indoline compound - Google Patents US9932308B2 -
Method for producing indoline compound - Google Patents Method for producing indoline …
Method for producing indoline compound - Google Patents Method for producing indoline …
Method for producing indoline compound
T Motoyama, K Takata, Y Fukuhara, M Uemura… - US Patent …, 2017 - Google Patents
Provided is a method for producing a compound represented by a formula (6), the method
comprising: a step of mixing a compound represented by a formula (4) and a compound …
comprising: a step of mixing a compound represented by a formula (4) and a compound …
Maleic acid salt of a silodosin intermediate
JLDELRÍO PERICACHO, XV Tusell - US Patent 10,421,719, 2019 - Google Patents
US10421719B2 - Maleic acid salt of a silodosin intermediate - Google Patents US10421719B2
- Maleic acid salt of a silodosin intermediate - Google Patents Maleic acid salt of a silodosin …
- Maleic acid salt of a silodosin intermediate - Google Patents Maleic acid salt of a silodosin …