Inhibitors of protein methyltransferases and demethylases
Post-translational modifications of histones by protein methyltransferases (PMTs) and
histone demethylases (KDMs) play an important role in the regulation of gene expression …
histone demethylases (KDMs) play an important role in the regulation of gene expression …
Histone methylation in higher plants
Histone methylation plays a fundamental role in regulating diverse developmental
processes and is also involved in silencing repetitive sequences in order to maintain …
processes and is also involved in silencing repetitive sequences in order to maintain …
[HTML][HTML] Comprehensive analysis of silencing mutants reveals complex regulation of the Arabidopsis methylome
H Stroud, MVC Greenberg, S Feng, YV Bernatavichute… - Cell, 2013 - cell.com
Cytosine methylation is involved in various biological processes such as silencing of
transposable elements (TEs) and imprinting. Multiple pathways regulate DNA methylation in …
transposable elements (TEs) and imprinting. Multiple pathways regulate DNA methylation in …
A DNA methylation reader complex that enhances gene transcription
DNA methylation generally functions as a repressive transcriptional signal, but it is also
known to activate gene expression. In either case, the downstream factors remain largely …
known to activate gene expression. In either case, the downstream factors remain largely …
A photoactivatable GFP for selective photolabeling of proteins and cells
GH Patterson, J Lippincott-Schwartz - Science, 2002 - science.org
We report a photoactivatable variant of the Aequorea victoria green fluorescent protein
(GFP) that, after intense irradiation with 413-nanometer light, increases fluorescence 100 …
(GFP) that, after intense irradiation with 413-nanometer light, increases fluorescence 100 …
Control of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase
Gene silencing in eukaryotes is associated with the formation of heterochromatin, a complex
of proteins and DNA that block transcription. Heterochromatin is characterized by the …
of proteins and DNA that block transcription. Heterochromatin is characterized by the …
Genome-wide analysis of mono-, di- and trimethylation of histone H3 lysine 4 in Arabidopsis thaliana
X Zhang, YV Bernatavichute, S Cokus, M Pellegrini… - Genome biology, 2009 - Springer
Background Post-translational modifications of histones play important roles in maintaining
normal transcription patterns by directly or indirectly affecting the structural properties of the …
normal transcription patterns by directly or indirectly affecting the structural properties of the …
Position-effect variegation, heterochromatin formation, and gene silencing in Drosophila
SCR Elgin, G Reuter - Cold Spring Harbor perspectives …, 2013 - cshperspectives.cshlp.org
Position-effect variegation (PEV) results when a gene normally in euchromatin is juxtaposed
with heterochromatin by rearrangement or transposition. When heterochromatin packaging …
with heterochromatin by rearrangement or transposition. When heterochromatin packaging …
p63 and p73 are required for p53-dependent apoptosis in response to DNA damage
The tumour-suppressor gene p53 is frequently mutated in human cancers and is important
in the cellular response to DNA damage,. Although the p53 family members p63 and p73 …
in the cellular response to DNA damage,. Although the p53 family members p63 and p73 …
Myo-inositol and beyond–emerging networks under stress
R Valluru, W Van den Ende - Plant science, 2011 - Elsevier
Myo-inositol is a versatile compound that generates diversified derivatives upon
phosphorylation by lipid-dependent and-independent pathways. Phosphatidylinositols form …
phosphorylation by lipid-dependent and-independent pathways. Phosphatidylinositols form …