Population balance modeling: current status and future prospects

D Ramkrishna, MR Singh - Annual review of chemical and …, 2014 - annualreviews.org
Population balance modeling is undergoing phenomenal growth in its applications, and this
growth is accompanied by multifarious reviews. This review aims to fortify the model's …

Scalable stirred-suspension bioreactor culture of human pluripotent stem cells

DE Kehoe, D Jing, LT Lock… - Tissue Engineering Part …, 2010 - liebertpub.com
Advances in stem cell biology have afforded promising results for the generation of various
cell types for therapies against devastating diseases. However, a prerequisite for realizing …

Experimental methods and modeling techniques for description of cell population heterogeneity

RL Fernandes, M Nierychlo, L Lundin… - Biotechnology …, 2011 - Elsevier
With the continuous development, in the last decades, of analytical techniques providing
complex information at single cell level, the study of cell heterogeneity has been the focus of …

A comprehensive review of computational cell cycle models in guiding cancer treatment strategies

C Ma, E Gurkan-Cavusoglu - NPJ Systems Biology and Applications, 2024 - nature.com
This article reviews the current knowledge and recent advancements in computational
modeling of the cell cycle. It offers a comparative analysis of various modeling paradigms …

Quantifying the length and variance of the eukaryotic cell cycle phases by a stochastic model and dual nucleoside pulse labelling

TS Weber, I Jaehnert, C Schichor… - PLoS computational …, 2014 - journals.plos.org
A fundamental property of cell populations is their growth rate as well as the time needed for
cell division and its variance. The eukaryotic cell cycle progresses in an ordered sequence …

Exponentially modified Gaussian (EMG) relevance to distributions related to cell proliferation and differentiation

A Golubev - Journal of theoretical biology, 2010 - Elsevier
Positively skewed distributions common in biology are often approximated with lognormal or
gamma functions. It is shown here that for some classes of phenomena, including …

Deconstructing stem cell population heterogeneity: single-cell analysis and modeling approaches

J Wu, ES Tzanakakis - Biotechnology advances, 2013 - Elsevier
Isogenic stem cell populations display cell-to-cell variations in a multitude of attributes
including gene or protein expression, epigenetic state, morphology, proliferation and …

Synchronisation and control of proliferation in cycling cell population models with age structure

F Billy, J Clairambaultt, O Fercoq, S Gaubertt… - … and Computers in …, 2014 - Elsevier
We present and analyse in this article a mathematical question with a biological origin, the
theoretical treatment of which may have far-reaching implications in the practical treatment …

Age-structured cell population model to study the influence of growth factors on cell cycle dynamics.

F Billy, J Clairambault, F Delaunay, CA Feillet… - Mathematical …, 2012 - hal.science
Cell proliferation is controlled by many complex regulatory networks. Ourpurpose is to
analyse, through mathematical modeling, the effects of growth factors on the dynamics of the …

Cognitive and behavioral outcomes from traumatic brain injury

J Griffen, R Hanks - Handbook on the neuropsychology of traumatic brain …, 2014 - Springer
Outcome following traumatic brain injury (TBI) depends on many factors, including severity
of injury. Research has demonstrated a dose–response relationship between TBI severity …