Histone deacetylase 3 regulates the inflammatory gene expression programme of rheumatoid arthritis fibroblast-like synoviocytes

C Angiolilli, PA Kabala, AM Grabiec… - Annals of the …, 2017 - ard.bmj.com
Objectives Non-selective histone deacetylase (HDAC) inhibitors (HDACi) have
demonstrated anti-inflammatory properties in both in vitro and in vivo models of rheumatoid …

[HTML][HTML] Association between purchase of over-the-counter medications and ovarian cancer diagnosis in the cancer loyalty card study (CLOCS): observational case …

HR Brewer, Y Hirst, M Chadeau-Hyam… - JMIR public health …, 2023 - publichealth.jmir.org
Background: Over-the-counter (OTC) medications are frequently used to self-care for
nonspecific ovarian cancer symptoms prior to diagnosis. Monitoring such purchases may …

[HTML][HTML] Understanding public attitudes and willingness to share commercial data for health research: survey study in the United Kingdom

Y Hirst, ST Stoffel, HR Brewer… - JMIR public health …, 2023 - publichealth.jmir.org
Background: Health research using commercial data is increasing. The evidence on public
acceptability and sociodemographic characteristics of individuals willing to share …

[HTML][HTML] Testing the effectiveness of an animated decision aid to improve recruitment of control participants in a case-control study: web-based experiment

ST Stoffel, JH Law, R Kerrison, HR Brewer… - Journal of Medical …, 2022 - jmir.org
Background Participation in case-control studies is crucial in epidemiological research. The
self-sampling bias, low response rate, and poor recruitment of population representative …

Using online search activity for earlier detection of gynaecological malignancy

JF Barcroft, E Yom-Tov, V Lampos, LB Ellis… - BMC public health, 2024 - Springer
Background Ovarian cancer is the most lethal and endometrial cancer the most common
gynaecological cancer in the UK, yet neither have a screening program in place to facilitate …

Overcoming biases of individual level shopping history data in health research

A Skatova - NPJ Digital Medicine, 2024 - nature.com
Novel sources of population data, especially administrative and medical records, as well as
the digital footprints generated through interactions with online services, present a …

[HTML][HTML] Using shopping data to improve the diagnosis of ovarian cancer: computational analysis of a web-based survey

EH Dolan, J Goulding, LJ Tata, AR Lang - JMIR cancer, 2023 - cancer.jmir.org
Background: Shopping data can be analyzed using machine learning techniques to study
population health. It is unknown if the use of such methods can successfully investigate …

Cancer Loyalty Card Study (CLOCS): feasibility outcomes for an observational case–control study focusing on the patient interval in ovarian cancer

HR Brewer, M Chadeau-Hyam, E Johnson, S Sundar… - BMJ open, 2023 - bmjopen.bmj.com
Objectives Ovarian cancer symptoms are often non-specific and can be normalised before
patients seek medical help. The Cancer Loyalty Card Study investigated self-management …

Seasonal purchase of antihistamines and ovarian cancer risk in the Cancer Loyalty Card Study (CLOCS): results from an observational case-control study

HR Brewer, Q Jiang, S Sundar, Y Hirst, JM Flanagan - medRxiv, 2023 - medrxiv.org
Objective Antihistamine use has previously been associated with a reduction in incidence of
ovarian cancer, particularly in pre-menopausal women. Herein, we investigate antihistamine …

Impact of pension income on healthcare utilization of older adults in rural China

P Yan, F Li, S Nicholas, E Maitland, J Tan… - International Journal for …, 2023 - Springer
Abstract Objective In China, rural residents experience poorer health conditions and a
higher disease burden compared to urban residents but have lower healthcare services …