Neuroinflammation has either beneficial or detrimental effects, depending on risk factors and
neuron–glia interactions in neurological disorders. However, studying neuroinflammation …

Despite the better understanding of the mechanisms underlying Alzheimer's Disease (AD)
and launched clinical trials, no AD-modifying treatment based on a synthetic drug has been …

Peripheral β-amyloid (Aβ), including those contained in the gut, may contribute to the
formation of Aβ plaques in the brain, and gut microbiota appears to exert an impact on …

Abstract Fine particulate matter (PM2. 5), a major component among air pollutants,
highlights as a global health concern. Several epidemiological studies show the correlation …

Background Masitinib is an orally administered tyrosine kinase inhibitor that targets
activated cells of the neuroimmune system (mast cells and microglia). Study AB09004 …

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive
cognitive decline and memory loss. While the precise causes of AD remain unclear …

Microglial neuroinflammation appears to be neuroprotective in the early pathological stage,
yet neurotoxic, which often precedes neurodegeneration in Alzheimer's disease (AD) …

It is widely recognized that Alzheimer's disease (AD) is a common type of progressive
neurodegenerative disorder that results in cognitive impairment over time. Approximately …

Porphyromonas gingivalis is a gram-negative bacterium found in the human oral cavity and
is responsible for the development of chronic periodontitis as well as neurological diseases …

Alzheimer's disease (AD) is a progressive, complex, and multifactorial neurodegenerative
disorder, still without effective and stable therapeutic strategies. Currently, available …