Our incomplete understanding of the causes and pathways involved in the onset and
progression of multiple sclerosis (MS) limits our ability to effectively treat this complex …

Neuroprotective and neurorestorative therapy represent two major drug intervention
strategies for ischemic stroke. Multiple factors such as excitotoxicity, inflammation …

Metabolic dysfunction-associated steatotic liver disease (MASLD) is an unabated risk factor
for end-stage liver diseases with no available therapies. Dysregulated immune responses …

Alzheimer's disease (AD), is a chronic age-related progressive neurodegenerative disorder,
characterized by neuroinflammation and extracellular aggregation of Aβ peptide …

Unconventional T cells include γδ T cells, invariant Natural Killer T cells (iNKT) cells and
Mucosal Associated Invariant T (MAIT) cells, which are distinguished from conventional T …

The interaction between peripheral immune cells and the brain is an important component of
the neuroimmune axis. Unconventional T cells, which include natural killer T (NKT) cells …

Multiple sclerosis (MS) is a chronic, autoimmune and neuroinflammatory disease of the
central nervous system (CNS) mediated by autoreactive T cells directed against myelin …

Stroke is a leading cause of mortality and long-term disability worldwide, with limited
spontaneous repair processes occurring after injury. Immune cells are involved in multiple …

Background Multiple sclerosis (MS) is a chronic, debilitating condition characterized by CNS
autoimmunity stemming from a complex etiology involving both environmental and genetic …

Farnesoid-X receptor (FXR), as a nuclear receptor activated by bile acids, is a vital molecule
involved in bile acid metabolism. Due to its expression in immune cells, FXR has a …