Obesity and obesity-associated disorders pose a major public health issue worldwide. Apart
from conventional weight loss drugs, next-generation probiotics (NGPs) seem to be very …

The role of Akkermansia muciniphila, one of the most abundant microorganisms of the
intestinal microbiota, has been studied extensively in metabolic diseases, such as obesity …

Outer membrane vesicles (OMVs) play vital roles in bacterial communication both
intraspecifically and interspecifically. However, extracellular mechanisms of gut microbiota …

Accumulating evidence indicates gut microbiota contributes to aging-related disorders.
However, the exact mechanism underlying gut dysbiosis-related pathophysiological …

Ischemic stroke is closely associated with gut microbiota dysbiosis and intestinal barrier
dysfunction. Prebiotic intervention could modulate the intestinal microbiota, thus considered …

Globally, metabolic diseases are becoming a major public health problem. Herbal
medicines are medicinal materials or preparations derived from plants and are widely used …

Akkermansia muciniphila (A. muciniphila) has been demonstrated to exhibit beneficial
effects against various metabolic diseases, but whether A. muciniphila has an anti …

The soluble dietary fiber polydextrose (PDX) is a randomly linked glucose oligomer
containing small amounts of sorbitol and citric acid and is widely used in the food industry …

Background Accumulating evidence suggests the role of brain–spleen axis as well as brain–
gut–microbiota axis in inflammation-related depression. The spleen mediates anti …

Metabolic disease is a worldwide epidemic that has become a public health problem. Gut
microbiota is considered to be one of the important factors that maintain human health by …