Skeletal muscle plays important roles in normal biological activities and whole-body energy
homeostasis in humans. The growth and development of skeletal muscle also directly …

Connective tissue growth factor (CTGF) is a distinct signaling molecule modulating many
physiological and pathophysiological processes. This protein is upregulated in numerous …

Lysophosphatidic acid (LPA) is a lysophospholipid that signals through six G-protein
coupled receptors (LPARs), LPA 1 to LPA 6. LPA has been described as a potent modulator …

Lysophosphatidic acid is a growth factor-like bioactive phospholipid recognising LPA
receptors and mediating signalling pathways that regulate embryonic development, wound …

Diabetic cardiomyopathy (DCM) is a specific type of myocardial disease that often develops
in patients suffering from diabetes, which has become the foremost cause of death among …

Skeletal muscle fibrosis is defined as the excessive accumulation of extracellular matrix
(ECM) components and is a hallmark of muscular dystrophies. Fibro-adipogenic progenitors …

Abstract Cellular Communication Network Factor 2, CCN2, is a profibrotic cytokine
implicated in physiological and pathological processes in mammals. The expression of …

Pdgfrα+ stromal cells are a group of cells specifically expressing Pdgfrα, which may be
mentioned with distinct names in different tissues. Importantly, the findings from numerous …

Binge Drinking (BD) corresponds to episodes of ingestion of large amounts of ethanol in a
short time, typically≤ 2 h. BD occurs across all populations, but young and sports-related …

We investigated how Interleukin 1 beta (IL-1β) impacts equine tenocyte function and global
gene expression in vitro and determined if these effects could be rescued by …