Apathy associated with neurocognitive disorders: recent progress and future directions

KL Lanctôt, L Agüera-Ortiz, H Brodaty, PT Francis… - Alzheimer's & …, 2017 - Elsevier
Introduction Apathy is common in neurocognitive disorders (NCDs) such as Alzheimer's
disease and mild cognitive impairment. Although the definition of apathy is inconsistent in …

Apathy: why care?

R Van Reekum, DT Stuss… - The Journal of …, 2005 - Am Neuropsych Assoc
This review presents data showing that apathy is common across a number of disorders.
Apathy is not only common, but is also associated with significant problems: reduced …

Neuropsychiatric symptoms in Alzheimer's disease

CG Lyketsos, MC Carrillo, JM Ryan… - Alzheimer's & …, 2011 - Elsevier
Neuropsychiatric symptoms (NPS) are core features of Alzheimer's disease and related
dementias. Once thought to emerge primarily in people with late-stage disease, these …

Methylphenidate: its pharmacology and uses

TD Challman, JJ Lipsky - Mayo Clinic Proceedings, 2000 - Elsevier
Methylphenidate is a commonly used medication in the United States. This central nervous
system stimulant has a mechanism of action distinct from that of amphetamine. The Food …

Methylphenidate: a review of its neuropharmacological, neuropsychological and adverse clinical effects.

BE Leonard, D McCartan, J White… - … Clinical and Experimental, 2004 - psycnet.apa.org
The purpose of this review is to consider the mechanism of action, pharmacological
properties and neuropsychological effects of methylphenidate. This has been stimulated by …

[PDF][PDF] Hypofrontality and negative symptoms in major depressive disorder

II Galynker, J Cai, F Ongseng, H Finestone… - Journal of Nuclear …, 1998 - Soc Nuclear Med
Additionally, there were positive correlations between HRSD scores and rCBF in the left
anterior temporal (r= 0.71, p< 0.01), left dorsolateral prefrontal (r= 0.70, p< 0.01), right frontal …

Characteristics of apathy in Parkinson's disease

K Dujardin, P Sockeel, D Devos, M Delliaux… - Movement …, 2007 - Wiley Online Library
The objective of this study was to use the Lille Apathy Rating Scale to assess apathy in a
large population of Parkinson's disease (PD) patients and identify several different apathy …

A phase III, double-blind, placebo-controlled prospective randomized clinical trial of d-threo-methylphenidate HCl in brain tumor patients receiving radiation therapy

JM Butler Jr, LD Case, J Atkins, B Frizzell… - International Journal of …, 2007 - Elsevier
PURPOSE: The quality of life (QOL) and neurocognitive function of patients with brain
tumors are negatively affected by the symptoms of their disease and brain radiation therapy …

Association between attention-deficit hyperactivity disorder in childhood and schizophrenia later in adulthood

S Dalsgaard, PB Mortensen, M Frydenberg… - European …, 2014 - cambridge.org
Purpose: To estimate the risk of schizophrenia in adulthood among children and
adolescents with ADHD compared to the background population. Subjects/materials and …

The role of dopamine in symptoms and treatment of apathy in Alzheimer's disease

RA Mitchell, N Herrmann… - CNS neuroscience & …, 2011 - Wiley Online Library
Background: Alzheimer's disease (AD) is characterized by a number of serious and
debilitating behavioral and psychological symptoms of dementia (BPSD). The most common …