How I prevent GVHD in high-risk patients: posttransplant cyclophosphamide and beyond

J Rimando, SR McCurdy, L Luznik - Blood, 2023 - ashpublications.org
Advances in conditioning, graft-versus-host disease (GVHD) prophylaxis and antimicrobial
prophylaxis have improved the safety of allogeneic hematopoietic cell transplantation (HCT) …

Donor clonal hematopoiesis and recipient outcomes after transplantation

CJ Gibson, HT Kim, L Zhao, HM Murdock… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE Clonal hematopoiesis (CH) can be transmitted from a donor to a recipient during
allogeneic hematopoietic cell transplantation. Exclusion of candidate donors with CH is …

Alternative donor BMT with posttransplant cyclophosphamide as initial therapy for acquired severe aplastic anemia

AE DeZern, M Zahurak, HJ Symons… - Blood, The Journal …, 2023 - ashpublications.org
Severe aplastic anemia (SAA) is a marrow failure disorder with high morbidity and mortality.
It is treated with bone marrow transplantation (BMT) for those with fully matched donors, or …

Signatures of GVHD and relapse after posttransplant cyclophosphamide revealed by immune profiling and machine learning

SR McCurdy, V Radojcic, HL Tsai… - Blood, The Journal …, 2022 - ashpublications.org
The key immunologic signatures associated with clinical outcomes after posttransplant
cyclophosphamide (PTCy)-based HLA-haploidentical (haplo) and HLA-matched bone …

Haploidentical stem cell transplantation for acute myeloid leukemia: current therapies, challenges and future prospective

YJ Chang, XY Zhao, XJ Huang - Frontiers in Oncology, 2021 - frontiersin.org
Haploidentical stem cell transplantation (haplo-SCT), an alternative donor source, offers a
curative therapy for patients with acute myeloid leukemia (AML) who are transplant …

Younger haploidentical donor versus older matched unrelated donor for patients with AML/MDS

C Marcoux, D Marin, J Ramdial… - American journal of …, 2023 - Wiley Online Library
Optimal donor selection is fundamental to successful allogeneic hematopoietic cell
transplantation (HCT), and donor age influences survival after both matched unrelated …

Hematology 2022—what is complete HLA match in 2022?

SR Spellman - Hematology, 2022 - ashpublications.org
Allogeneic hematopoietic cell transplantation (alloHCT) often represents the only curative
treatment for various malignant and nonmalignant disorders. Initially, the only suitable …

HLA-matching with PTCy: a reanalysis of a CIBMTR dataset with propensity score matching and donor age

A Ambinder, T Jain, HL Tsai, MM Horowitz… - Blood …, 2022 - ashpublications.org
Blood or marrow transplantation (BMT) outcomes using haploidentical donors (Haplo) and
posttransplant cyclophosphamide (PTCy)-based graft-versus-host disease (GVHD) …

[HTML][HTML] Existence of HLA-mismatched unrelated donors closes the gap in donor availability regardless of recipient ancestry

AS Chowdhury, M Maiers, SR Spellman… - … and cellular therapy, 2023 - Elsevier
In patients without a matched sibling donor (MSD) or well-matched unrelated donor (MUD),
hematopoietic cell transplantation (HCT) can still be successful when using an HLA …

Donor types and outcomes of transplantation in myelofibrosis: a CIBMTR study

T Jain, N Estrada-Merly, MQ Salas, S Kim… - Blood …, 2024 - ashpublications.org
We evaluate the impact of donor types on outcomes of hematopoietic cell transplantation
(HCT) in myelofibrosis, using the Center for International Blood and Marrow Transplant …