The role of diet in multiple sclerosis: mechanistic connections and current evidence

I Katz Sand - Current nutrition reports, 2018 - Springer
Abstract Purpose of Review This review seeks to examine current research related to the
role of diet in multiple sclerosis (MS). Recent Findings Recent research in preclinical …

Targeting NF-κB signaling pathway in cancer by dietary polyphenols

H Khan, H Ullah, PCMF Castilho… - Critical Reviews in …, 2020 - Taylor & Francis
Being a transcription factor, NF-κB regulates gene expressions involving cell survival and
proliferation, drug resistance, metastasis, and angiogenesis. The activation of NF-κB plays a …

Motor behavioral deficits in the cuprizone model: Validity of the rotarod test paradigm

C Lubrich, P Giesler, M Kipp - International journal of molecular sciences, 2022 - mdpi.com
Multiple Sclerosis (MS) is a neuroinflammatory disorder, which is histopathologically
characterized by multifocal inflammatory demyelinating lesions affecting both the central …

Immunomodulatory potential of flavonoids for the treatment of autoimmune diseases and tumour

L Han, Q Fu, C Deng, L Luo, T Xiang… - … Journal of Immunology, 2022 - Wiley Online Library
The immune system plays an indispensable role in maintaining human health against the
invasion of foreign materials, microorgainisms and pathogens. The autoimmune diseases …

Behavioural phenotypes in the cuprizone model of central nervous system demyelination

MK Sen, DA Mahns, JR Coorssen… - … & Biobehavioral Reviews, 2019 - Elsevier
The feeding of cuprizone (CPZ) to animals has been extensively used to model the
processes of demyelination and remyelination, with many papers adopting a narrative linked …

MIND diet adherence might be associated with a reduced odds of multiple sclerosis: results from a case–control study

M Noormohammadi, Z Ghorbani… - Neurology and …, 2022 - Springer
Abstract Introduction The Mediterranean Dietary Approaches to the Stop Hypertension
(DASH) Intervention for Neurodegenerative Delay (MIND) diet has been shown to have …

Voluntary running wheel attenuates motor deterioration and brain damage in cuprizone-induced demyelination

G Mandolesi, S Bullitta, D Fresegna, F De Vito… - Neurobiology of …, 2019 - Elsevier
Growing data from human and animal studies indicate the beneficial effects of exercise on
several clinical outcomes in patients with multiple sclerosis (MS), an autoimmune …

TRPV4 inhibition improved myelination and reduced glia reactivity and inflammation in a cuprizone-induced mouse model of demyelination

M Liu, X Liu, L Wang, Y Wang, F Dong, J Wu… - Frontiers in cellular …, 2018 - frontiersin.org
The inhibition of demyelination and the promotion of remyelination are both considerable
challenges in the therapeutic process for many central nervous system (CNS) diseases …

Baicalin promotes CNS remyelination via PPARγ signal pathway

RS Ai, K Xing, X Deng, JJ Han, DX Hao… - Neurology …, 2022 - AAN Enterprises
Background and Objectives Demyelinating diseases in the CNS are characterized by myelin
sheath destruction or formation disorder that leads to severe neurologic dysfunction …

Scutellaria baicalensis and its constituents baicalin and baicalein as antidotes or protective agents against chemical toxicities: a comprehensive review

A Ahmadi, Z Mortazavi, S Mehri… - … Archives of Pharmacology, 2022 - Springer
Scutellaria baicalensis (SB), also known as the Chinese skullcap, has a long history of being
used in Chinese medicine to treat a variety of conditions ranging from microbial infections to …