Owing to the environmental friendliness and vast advantages that enzymes offer in the
biotechnology and industry fields, biocatalysts are a prolific investigation field. However, the …

Deep mutational scanning (DMS) has recently emerged as a powerful method to study
protein sequence–function relationships but is not well-explored as a guide to enzyme …

Phenylalanine ammonia lyase (PAL) catalyzes the reversible conversion of l-phenylalanine
into the corresponding trans-cinnamic acid, providing a route to optically pure α-amino …

Phenylalanine ammonia-lyase (PAL) plays a pivotal role in the biosynthesis of
phenylalanine. PAL from Zea mays (ZmPAL2) exhibits a bi-function of direct deamination of …

In this study, rational design and saturation mutagenesis efforts for engineering
phenylalanine ammonia-lyase from Petroselinum crispum (Pc PAL) provided tailored PALs …

Phenylalanine ammonia-lyases (PALs) catalyse the non-oxidative deamination of L-
phenylalanine to trans-cinnamic acid, while in the presence of high ammonia concentration …

Phenylalanine ammonia‐lyase (PAL) is a crucial enzyme for various biotechnology
applications, such as producing phenols, antioxidants, and nutraceuticals. However …

An efficient preparative-scale synthetic procedure of l-phenylalanine derivatives has been
developed using mutant variants of phenylalanine ammonia-lyase from Arabidopsis thaliana …

Phenylalanine ammonia-lyases (PALs) catalyse the non-oxidative deamination of l-
phenylalanine to trans-cinnamic acid, while in the presence of high ammonia concentration …

In this study we assessed the applicability of the recently reported ancestral l-amino acid
oxidase (AncLAAO), for the development of an enzyme-coupled phenylalanine ammonia …