Synthesis and pharmacological activities of pyrazole derivatives: A review

K Karrouchi, S Radi, Y Ramli, J Taoufik, YN Mabkhot… - Molecules, 2018 - mdpi.com
Pyrazole and its derivatives are considered a pharmacologically important active scaffold
that possesses almost all types of pharmacological activities. The presence of this nucleus in …

Biological activity of ionic liquids and their application in pharmaceutics and medicine

KS Egorova, EG Gordeev, VP Ananikov - Chemical reviews, 2017 - ACS Publications
Ionic liquids are remarkable chemical compounds, which find applications in many areas of
modern science. Because of their highly tunable nature and exceptional properties, ionic …

The role of ionic liquids in the pharmaceutical field: An overview of relevant applications

SN Pedro, CS R. Freire, AJD Silvestre… - International journal of …, 2020 - mdpi.com
Solubility, bioavailability, permeation, polymorphism, and stability concerns associated to
solid-state pharmaceuticals demand for effective solutions. To overcome some of these …

Recent advancements in applications of ionic liquids in synthetic construction of heterocyclic scaffolds: A spotlight

TM Dhameliya, PR Nagar, KA Bhakhar… - Journal of Molecular …, 2022 - Elsevier
Heterocycles constitute the integral part of the most of United States food and drug
administration (USFDA) approved drugs. Over the past decade, ionic liquids have emerged …

Recent advances in the synthesis of pyrazole derivatives: a review

I Ameziane El Hassani, K Rouzi, H Assila, K Karrouchi… - Reactions, 2023 - mdpi.com
Pyrazole, characterized by a five-membered heterocyclic structure featuring two neighboring
nitrogen atoms, serves as a core element. Pyrazoles hold a privileged status as versatile …

Recent progress in anticancer agents incorporating pyrazole scaffold

S Mor, M Khatri, R Punia… - Mini Reviews in Medicinal …, 2022 - benthamdirect.com
The search for new anticancer agents is considered a dynamic field of medicinal chemistry.
In recent years, the synthesis of compounds with anticancer potential has increased and a …

Chalcones as Versatile Synthons for the Synthesis of 5-and 6-membered Nitrogen Heterocycles

H MT Albuquerque, C MM Santos… - Current Organic …, 2014 - ingentaconnect.com
Chalcones belong to the flavonoid family which constitutes one of the major classes of
naturally occurring oxygen heterocyclic compounds. The α, β-unsaturated carbonyl system …

Brønsted acidic ionic liquid-catalyzed tandem reaction: an efficient approach towards regioselective synthesis of pyrano [3, 2-c] coumarins under solvent-free …

S Mahato, S Santra, R Chatterjee, GV Zyryanov… - Green …, 2017 - pubs.rsc.org
1-Butane sulfonic acid-3-methylimidazolium tosylate,[BSMIM] OTs, is found to be a
remarkable catalyst for the tandem cyclization of 4-hydroxycoumarin with chalcones for the …

Ionic liquids in cationic polymerization: A review

IA Berezianko, SV Kostjuk - Journal of Molecular Liquids, 2024 - Elsevier
This article reviews a progress reached in application of neutral and acidic ionic liquids (ILs)
in cationic polymerization processes. The whole subject was divided into two parts:(i) neutral …

[HTML][HTML] Substituted pyrazoles and their heteroannulated analogs—recent syntheses and biological activities

M Ramadan, AA Aly, LEA El-Haleem, MB Alshammari… - Molecules, 2021 - mdpi.com
Pyrazoles are considered privileged scaffolds in medicinal chemistry. Previous reviews have
discussed the importance of pyrazoles and their biological activities; however, few have …