Adult neurogenesis occurs mainly in the subgranular zone of the hippocampal dentate gyrus
and the subventricular zone of the lateral ventricles. Evidence supports the critical role of …

In adult brain, new neurons are generated throughout adulthood in the subventricular zone
and the dentate gyrus; this process is commonly known as adult neurogenesis. The …

Background Alzheimer's disease (AD) is a neurodegenerative disease characterized by a
progressive decline in cognitive ability. Exosomes derived from bone-marrow mesenchymal …

Human aging affects the entire organism, but aging of the brain must undoubtedly be
different from that of all other organs, as neurons are highly differentiated postmitotic cells …

Alzheimer's disease (AD) is the most common form of dementia and seriously affects the
quality of life of the elderly. Neurodegeneration is closely related to hippocampal dysfunction …

Alzheimer's disease (AD) is characterized by progressive cognitive decline including
memory impairment, cortical dysfunction, and neuropsychiatric disturbances. The drug …

Aims The relationship between type 2 diabetes and Alzheimer's disease (AD) provides
evidence that insulin and insulin sensitizers may be beneficial for the treatment of AD. The …

The objective of the present study was to investigate the α7nAChR-mediated Nrf2-
dependant protective activity against streptozotocin (STZ)-induced brain mitochondrial …

Alzheimer's disease (AD) is a neurodegenerative disorder clinically manifested by a gradual
cognitive decline. Intracerebroventricular injection (ICV) of streptozotocin (STZ), a model of …

The earliest hallmarks of sporadic Alzheimer's disease (sAD) are impaired glucose
metabolism, chronic neuroinflammation, diminished synaptic plasticity and subsequent …