Single cell optical imaging and spectroscopy

AS Stender, K Marchuk, C Liu, S Sander… - Chemical …, 2013 - ACS Publications
In his 1665 treatise, Micrographia, Robert Hooke described the many observations he had
made using a microscope, including compartment-like structures in cork samples that he …

Interplay between lipid metabolism, lipid droplets, and DNA virus infections

MA Farías, B Diethelm-Varela, AJ Navarro, AM Kalergis… - Cells, 2022 - mdpi.com
Lipid droplets (LDs) are cellular organelles rich in neutral lipids such as triglycerides and
cholesterol esters that are coated by a phospholipid monolayer and associated proteins …

Review of optical methods for noninvasive imaging of skin fibroblasts—From in vitro to ex vivo and in vivo visualization

VV Nikolaev, YV Kistenev, M Kröger… - Journal of …, 2024 - Wiley Online Library
Fibroblasts are among the most common cell types in the stroma responsible for creating
and maintaining the structural organization of the extracellular matrix in the dermis, skin …

Simultaneous, label-free, multispectral fluorescence lifetime imaging and optical coherence tomography using a double-clad fiber

BE Sherlock, JE Phipps, J Bec, L Marcu - Optics letters, 2017 - opg.optica.org
We present a novel fiber-based imaging platform that allows simultaneous fluorescence
lifetime imaging (FLIm) and optical coherence tomography (OCT) using a double-clad fiber …

Integrated multimodal optical microscopy for structural and functional imaging of engineered and natural skin

Y Zhao, BW Graf, EJ Chaney… - Journal of …, 2012 - Wiley Online Library
An integrated multimodal optical microscope is demonstrated for high‐resolution, structural
and functional imaging of engineered and natural skin. This microscope incorporates …

LipiD-QuanT: a novel method to quantify lipid accumulation in live cells [S]

H Varinli, MJ Osmond-McLeod, PL Molloy… - Journal of lipid …, 2015 - ASBMB
Lipid droplets (LDs) are the main storage organelles for triglycerides. Elucidation of lipid
accumulation mechanisms and metabolism are essential to understand obesity and …

Multimodal nonlinear optical imaging for sensitive detection of multiple pharmaceutical solid-state forms and surface transformations

D Novakovic, J Saarinen, T Rojalin… - Analytical …, 2017 - ACS Publications
Two nonlinear imaging modalities, coherent anti-Stokes Raman scattering (CARS) and sum-
frequency generation (SFG), were successfully combined for sensitive multimodal imaging …

Single-cell level methods for studying the effect of antibiotics on bacteria during infection

K Kogermann, M Putrinš, T Tenson - European Journal of Pharmaceutical …, 2016 - Elsevier
Considerable evidence about phenotypic heterogeneity among bacteria during infection has
accumulated during recent years. This heterogeneity has to be considered if the …

Imaging and tracking of bone marrow-derived immune and stem cells

Y Zhao, AJ Bower, BW Graf, MD Boppart… - Imaging and Tracking …, 2013 - Springer
Bone marrow (BM)-derived stem and immune cells play critical roles in maintaining the
health, regeneration, and repair of many tissues. Given their important functions in tissue …

Insights into Caco-2 cell culture structure using coherent anti-Stokes Raman scattering (CARS) microscopy

J Saarinen, E Sözeri, SJ Fraser-Miller… - International journal of …, 2017 - Elsevier
We have used coherent anti-Stokes Raman scattering (CARS) microscopy as a novel and
rapid, label-free and non-destructive imaging method to gain structural insights into live …