Abstract Streptococcus pyogenes (Group A Streptococcus; GAS) is exquisitely adapted to
the human host, resulting in asymptomatic infection, pharyngitis, pyoderma, scarlet fever or …

In recent years, a population of unconventional T cells called 'mucosal-associated invariant
T cells'(MAIT cells) has captured the attention of immunologists and clinicians due to their …

T cell lineages are defined by specialized functions and differential expression of surface
antigens, cytokines and transcription factors. Conventional CD4+ and CD8+ T cells are the …

Human skin functions as a physical, chemical, and immune barrier against the external
environment while also providing a protective niche for its resident microbiota, known as the …

Mucosal-associated invariant T (MAIT) cells are an evolutionarily conserved T cell subset,
which reacts to most bacteria through T cell receptor (TCR)-mediated recognition of …

Mucosal-associated invariant T (MAIT) cells have been attracting increasing attention over
the last few years as a potent unconventional T cell subset. Three factors largely account for …

Mucosa-associated invariant T (MAIT) cells are a large innate-like T-cell subset in humans
defined by invariant TCR Vα7. 2 use and expression of CD161. MAIT cells recognize …

The human body frequently encounters harmful bacterial pathogens and employs immune
defense mechanisms designed to counteract such pathogenic assault. In the adaptive …

Mucosal-associated invariant T (MAIT) cells detect microbial infection via recognition of
riboflavin-based antigens presented by the major histocompatibility complex class I (MHC-I) …

MHC antigen presentation plays a fundamental role in adaptive and semi-invariant T cell
immunity. Distinct MHC molecules bind antigens that differ in chemical structure, origin and …