Introduction: The hybridization of biologically active molecules is a powerful tool for drug
discovery used to target a variety of diseases. It offers the prospect of better drugs for the …

Diabetes Mellitus (DM) is the fastest growing metabolic disorder affecting about 387 million
people across the globe and is estimated to affect 592 million people by year 2030. The …

Naturally occurring coumarins, having wide spectrum of activities such as antioxidant, anti-
inflammatory, anticancer, MAO-B inhibitory and antimicrobial, are frequently used by the …

In recent years, widespread outbreak of numerous infectious diseases across the globe has
created havoc among the population. Particularly, the inhabitants of tropical and sub-tropical …

Coumarins are fused benzene and pyrone ring systems with a wide spectrum of
bioactivities, including antitumor, anti‐inflammation, antiviral, and antibacterial effects. In this …

Cardiovascular diseases are the leading cause of death affecting 17.3 million people across
the globe and are estimated to affect 23.3 million people by year 2030. In recent years …

The increasing interest on new drug discovery is constantly up to date as drugs do not
increase survival adequately against increasing cancer cases worldwide. Based on the …

Naturally and synthetically derived hybrid molecules are an attractive source for therapeutic
agent development due to their dual or multiple modes of action and other advantages …

Density functional theory (DFT) and time-dependent formulation of DFT (TDDFT) have been
employed to elucidate the structural characteristics, the antioxidant ability, and the UV-Vis …

Phyto-coumarins demonstrate diverse biological actions, encompassing antiradical, anti-
inflammatory, oncolytic, monoamine oxidase B (MAOB) suppression, and antibacterial …