The extracellular vesicle–macrophage regulatory axis: A novel pathogenesis for endometriosis

X Gao, H Gao, W Shao, J Wang, M Li, S Liu - Biomolecules, 2023 - mdpi.com
Endometriosis (EMs) is a common disease among women whose pathogenesis is still
unclear, although there are various hypotheses. Recent studies have considered …

The nucleolus, an ally, and an enemy of cancer cells

D Stępiński - Histochemistry and cell biology, 2018 - Springer
The rates of ribosome production by a nucleolus and of protein biosynthesis by ribosomes
are tightly correlated with the rate of cell growth and proliferation. All these processes must …

New roles for the nucleolus in health and disease

L Núñez Villacís, MS Wong, LL Ferguson, N Hein… - …, 2018 - Wiley Online Library
Over the last decade, our appreciation of the importance of the nucleolus for cellular function
has progressed from the ordinary to the extraordinary. We no longer think of the nucleolus …

Proteomic analysis of exosome-enriched fractions derived from cerebrospinal fluid of amyotrophic lateral sclerosis patients

N Hayashi, H Doi, Y Kurata, H Kagawa, Y Atobe… - Neuroscience …, 2020 - Elsevier
Exosomes contain many proteins associated with neurodegenerative diseases. To identify
new candidate biomarkers and proteins associated with amyotrophic lateral sclerosis (ALS) …

Long non-coding RNAs in esophageal cancer: molecular mechanisms, functions, and potential applications

M Su, Y Xiao, J Ma, D Cao, Y Zhou, H Wang… - Journal of hematology & …, 2018 - Springer
Esophageal cancer (EC) is the sixth leading cause of cancer-related death worldwide. The
lack of early diagnostic biomarkers and effective prognostic indicators for metastasis and …

Essential roles of E3 ubiquitin ligases in p53 regulation

S Sane, K Rezvani - International journal of molecular sciences, 2017 - mdpi.com
The ubiquitination pathway and proteasomal degradation machinery dominantly regulate
p53 tumor suppressor protein stability, localization, and functions in both normal and …

Proteome analysis in PAM cells reveals that African swine fever virus can regulate the level of intracellular polyamines to facilitate its own replication through ARG1

Q Ai, X Lin, H Xie, B Li, M Liao, H Fan - Viruses, 2021 - mdpi.com
In 2018, African swine fever broke out in China, and the death rate after infection was close
to 100%. There is no effective and safe vaccine in the world. In order to better characterize …

RSL1D1 modulates cell senescence and proliferation via regulation of PPARγ mRNA stability

Z Jiang, F Hao, F Zhu, F Yuan, L Ma, G Li, J Chen… - Life Sciences, 2022 - Elsevier
Aims In this study, we will examine if RSL1D1 influences PPARγ expression and explore the
underlying mechanism that RSL1D1 regulates PPARγ expression. Moreover, the …

The long non-coding RNA AK001796 contributes to tumor growth via regulating expression of p53 in esophageal squamous cell carcinoma

B Liu, CF Pan, GL Yao, K Wei, Y Xia, YJ Chen - Cancer cell international, 2018 - Springer
Background Esophageal squamous cell carcinoma (ESCC) is one of the prevalent and
deadly cancers worldwide, especially in China. Considering the poor prognosis of ESCC …

MDM2-p53 interactions in human hepatocellular carcinoma: what is the role of nutlins and new therapeutic options?

SA Azer - Journal of Clinical Medicine, 2018 - mdpi.com
Human hepatocellular carcinoma (HCC) is the fifth most common cancer and is associated
with poor prognosis worldwide. The molecular mechanisms underlying the pathogenesis of …