Ovarian cancer is the deadliest gynecological cancer, leading to over 152,000 deaths each
year. A late diagnosis is the primary factor causing a poor prognosis of ovarian cancer and …

Financial Disclosure Prof. Menon has stock ownership and has received research funding
from Abcodia Ltd, a UCL spinout company with an interest in biomarkers and commercial …

Simple Summary Ovarian high-grade serous carcinoma (HGSC) has a 5-year survival rate
of less than 50%, making it one of the most lethal gynecological cancers for women in the …

Ovarian cancer is the third most common gynaecological malignancy and the most lethal
worldwide. Most patients are diagnosed with advanced disease which carries significant …

The rationale for early detection of ovarian cancer is compelling. Ovarian cancer confined to
the ovaries (stage I) can be cured in up to 90% of patients, and disease confined to the …

Early detection of ovarian cancer remains an important unmet medical need. Effective
screening could reduce mortality by 10%–30%. Used individually, neither serum CA125 nor …

Abstract Purpose of Review Both conventional and novel approaches to early detection of
ovarian cancer are reviewed in the context of new developments in our understanding of …

Simple Summary Cancer is one of the main causes of death worldwide and early detection
is crucial for effective treatment. Scientists have therefore focused on the identification of …

The aim of this study was to develop a noninvasive serological diagnostic approach in
identifying and evaluating a panel of candidate autoantibodies to tumor‐associated antigens …

TP53 is the most commonly mutated gene in cancer and has been shown to form amyloid-
like aggregates, similar to key proteins in neurodegenerative diseases. Nonetheless, the …