The landscape of clinical trials in corneal regeneration: A systematic review of tissue engineering approaches in corneal disease

S Boroumand, M Rahmani, F Sigaroodi… - … Research Part B …, 2024 - Wiley Online Library
The limited availability of a healthy donor cornea and the incidence of allograft failure led
researchers to seek other corneal substitutes via tissue engineering. Exploring the trend of …

Limbal epithelial and mesenchymal stem cell therapy for corneal regeneration

S Shukla, SS Shanbhag, F Tavakkoli, S Varma… - Current eye …, 2020 - Taylor & Francis
Corneal pathologies are a major cause of blindness and visual impairment, especially in the
developing world. However, not only is there a global shortage of donor corneal tissue, but a …

Impact of keratocyte differentiation on corneal opacity resolution and visual function recovery in male rats

AK Riau, Z Look, GHF Yam, C Boote, Q Ma… - Nature …, 2024 - nature.com
Intrastromal cell therapy utilizing quiescent corneal stromal keratocytes (qCSKs) from human
donor corneas emerges as a promising treatment for corneal opacities, aiming to overcome …

Biosynthetic alternatives for corneal transplant surgery

M Griffith, BK Poudel, K Malhotra, N Akla… - Expert Review of …, 2020 - Taylor & Francis
Introduction Corneal transplantation surgery faces several fundamental problems, including
graft failure, especially in complicated cases, and a marked shortage of human donor …

Pre-clinical evaluation of efficacy and safety of human limbus-derived stromal/mesenchymal stem cells with and without alginate encapsulation for future clinical …

M Damala, A Sahoo, N Pakalapati, V Singh, S Basu - Cells, 2023 - mdpi.com
Corneal opacification or scarring is one of the leading causes of blindness worldwide.
Human limbus-derived stromal/mesenchymal stem cells (hLMSCs) have the potential of …

The role of eye banking with cell-based therapies

LT Tran, JY Li - Current Opinion in Ophthalmology, 2023 - journals.lww.com
The role of eye banking with cell-based therapies : Current Opinion in Ophthalmology The role
of eye banking with cell-based therapies : Current Opinion in Ophthalmology Log in or Register …

Encapsulation of human limbus-derived stromal/mesenchymal stem cells for biological preservation and transportation in extreme Indian conditions for clinical use

M Damala, S Swioklo, MA Koduri, NS Mitragotri… - Scientific Reports, 2019 - nature.com
Human limbus-derived stromal/mesenchymal stem cells (hLMSC) can be one of the
alternatives for the treatment of corneal scars. However, reliable methods of storing and …

Emerging approaches for ocular surface regeneration

G Yazdanpanah, S Jabbehdari, AR Djalilian - Current ophthalmology …, 2019 - Springer
Abstract Purpose of Review In this manuscript, the recent advancements and novel
approaches for regeneration of the ocular surface are summarized. Recent Findings …

The Human Cornea: Unraveling Its Structural, Chemical, and Biochemical Complexities

AK Raut, S Mohapatra, G SiddiquI, SK Rajak… - Chemistry & … - Wiley Online Library
The cornea, the transparent part of the anterior eye, is vital for light refraction and vision. This
review examines the intricate chemical and biochemical interactions essential for …

[PDF][PDF] Safety and toxicity of human limbus-derived stromal/mesenchymal stem cells with and without alginate encapsulation for clinical application

M Damala, N Pakalapati, V Singh, S Basu - 2021 - scholar.archive.org
Safety and toxicity of human limbus-derived stromal/mesenchymal stem cells with and without
alginate encapsulation for clinical Page 1 Page 1/29 Safety and toxicity of human …