Nuclear medicine application of pentixafor/pentixather targeting CXCR4 for imaging and therapy in related disease

Z Chen, Q Xue, S Yao - Mini Reviews in Medicinal Chemistry, 2023 - ingentaconnect.com
CXC-motif chemokine receptor 4 (CXCR4) is a novel predictive biomarker for metastasis
and poor prognosis in individuals with malignancies. CXCL12 is the only cognate ligand of …

CXCR4 PET/MRI for follow-up of gastric mucosa–associated lymphoid tissue lymphoma after first-line Helicobacter pylori eradication

ME Mayerhoefer, M Raderer, W Lamm… - Blood, The Journal …, 2022 - ashpublications.org
Posttreatment evaluation of gastric mucosa-associated lymphoid tissue (MALT) lymphoma
currently relies on esophagogastroduodenoscopy with histological assessment of biopsies …

[HTML][HTML] CXCR4 PET imaging of mantle cell lymphoma using [68Ga] Pentixafor: comparison with [18F] FDG-PET

ME Mayerhoefer, M Raderer, W Lamm, V Pichler… - Theranostics, 2021 - ncbi.nlm.nih.gov
For PET imaging of mantle cell lymphoma (MCL),[18 F] FDG (2-deoxy-2-[18 F] fluoro-D-
glucose) is the currently recommended radiotracer, although uptake is variable and bone …

Prognostic significance of 68Ga-Pentixafor PET/CT in multiple myeloma recurrence: a comparison to 18F-FDG PET/CT and laboratory results

S Kuyumcu, EG Isik, TO Tiryaki, D Has-Simsek… - Annals of nuclear …, 2021 - Springer
Purpose This study investigates the prognostic value of 68Ga-Pentixafor PET/CT using PET-
derived quantitative in multiple myeloma (MM) patients with suspected recurrence in …

Preliminary evidence of imaging of chemokine receptor-4-targeted PET/CT with [68Ga]pentixafor in non-Hodgkin lymphoma: comparison to [18F]FDG

Q Pan, Y Luo, Y Zhang, L Chang, J Li, X Cao, J Li, F Li - EJNMMI research, 2020 - Springer
Background In order to study the CXCR4 expression with [68 Ga] pentixafor PET in different
types of non-Hodgkin lymphoma, we performed a retrospective study to describe the [68 Ga] …

Intense 68Ga-pentixafor activity in aldosterone-producing adrenal adenomas

J Ding, A Tong, Y Zhang, J Wen… - Clinical Nuclear Medicine, 2020 - journals.lww.com
Abstract 68 Ga-pentixafor, a ligand of CXCR4 (CXC chemokine receptor type 4), has been
reported as a potential PET tracer to evaluate a variety of pathological entities. We report …

Pulmonary cryptococcosis accidentally detected by 68Ga-Pentixafor PET/CT in a patient with multiple myeloma

Q Pan, Y Luo, X Cao, J Li, F Li - Clinical Nuclear Medicine, 2020 - journals.lww.com
Abstract 68 Ga-pentixafor PET/CT in a 66-year-old woman with newly diagnosed multiple
myeloma showed extensive disease in bone and bone marrow. After 6 cycles of …

[68Ga]-Pentixafor PET/CT imaging of lymphoproliferative malignancies

S Kuyumcu, MY Kıran, E Apaydın Arıkan… - Clinical and …, 2021 - Springer
Abstract Purpose This report evaluates [68Ga]-Pentixafor and [18F]-FDG PET/CT uptake
patterns of patients with lymphoproliferative malignancies. Methods Patients with non …

[18F]FDG PET/CT in a Case of Mycosis Fungoides Showing an Unusual Adverse Reaction to Mogamulizumab: Correlation Between Imaging and Histological …

L Filippi, I Proietti, V Petrozza, S Aversa… - Cancer Biotherapy & …, 2023 - liebertpub.com
A 73-year-old female patient, affected by mycosis fungoides (MF), discontinued
mogamulizumab, after initial clinical benefit, due to the onset of generalized erythema …

CXCR4 expression demonstrated by 68Ga-pentixafor PET/CT imaging in a case of systemic mastocytosis mimicking lymphoma

MY Kiran, EA Arikan, Y Sanli, G Yegen… - Clinical Nuclear …, 2021 - journals.lww.com
Abstract 68 Ga-Pentixafor is a novel radiotracer for imaging chemokine receptor subtype 4
(CXCR4) receptors, which are expressed exceptionally high in several hematologic …