[HTML][HTML] FSCN1 acts as a promising therapeutic target in the blockade of tumor cell motility: a review of its function, mechanism, and clinical significance

Z Li, J Shi, N Zhang, X Zheng, Y Jin, S Wen… - Journal of …, 2022 - ncbi.nlm.nih.gov
Fascin actin-bundling protein 1 (FSCN1) is an actin-bundling protein that is capable of
inducing membrane protrusions and plays critical roles in cell migration, motility, adhesion …

Targeting mitochondrial dysfunction with elamipretide

C Obi, AT Smith, GJ Hughes, AA Adeboye - Heart failure reviews, 2022 - Springer
Although currently employed therapies for heart failure decrease overall mortality and
improve patient quality of life temporarily, the disease is known to progress even for patients …

Selenium nanoparticles and quercetin suppress thioacetamide‐induced hepatocellular carcinoma in rats: Attenuation of inflammation involvement

AA Mohamed, RA Zaghloul… - … of Biochemical and …, 2022 - Wiley Online Library
The current study investigates the anti‐inflammatory and hepatoprotective effects of
selenium (Se) formulated as nanoparticles (SeNPs) and in combination with quercetin …

Antitumor effect of FGFR inhibitors on a novel cholangiocarcinoma patient derived xenograft mouse model endogenously expressing an FGFR2-CCDC6 fusion …

Y Wang, X Ding, S Wang, CD Moser, HM Shaleh… - Cancer letters, 2016 - Elsevier
Cholangiocarcinoma is a highly lethal cancer with limited therapeutic options. Recent
genomic analysis of cholangiocarcinoma has revealed the presence of fibroblast growth …

Biochemical and pathophysiological improvements in rats with thioacetamide induced-hepatocellular carcinoma using aspirin plus vitamin C

RR El Sadda, ZR Elshahawy, EA Saad - BMC cancer, 2023 - Springer
Background Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related
death, so we should be concerned and look for effective/less-harmful treatments than …

Oleuropein potentiates anti-tumor activity of cisplatin against HepG2 through affecting proNGF/NGF balance

IO Sherif, MMH Al-Gayyar - Life sciences, 2018 - Elsevier
Aims Oleuropein is considered as a new chemotherapeutic agent in human hepatocellular
carcinoma (HCC) while, its exact underlying molecular mechanism still not yet explored. In …

WRH-2412 alleviates the progression of hepatocellular carcinoma through regulation of TGF-β/β-catenin/α-SMA pathway

MAF Elewa, WM Eldehna, AME Hamdan… - Journal of Enzyme …, 2023 - Taylor & Francis
Hepatocellular carcinoma is considered one of the most lethal cancers, which is
characterised by increasing prevalence associated with high level of invasion and …

Doxycycline protects against ROS-induced mitochondrial fragmentation and ISO-induced heart failure

A Riba, L Deres, K Eros, A Szabo, K Magyar… - PLoS …, 2017 - journals.plos.org
In addition to their anti-bacterial action, tetracyclines also have complex biological effects,
including the modification of mitochondrial protein synthesis, metabolism and gene …

[HTML][HTML] Chemosensitizing effect of Alpinia officinarum rhizome extract in cisplatin-treated rats with hepatocellular carcinoma

SA Abass, NM Abdel-Hamid, TK Abouzed… - Biomedicine & …, 2018 - Elsevier
This study was conducted to estimate the preventing and sensitizing efficiency of Alpinia
officinarum rhizome extract (AORE) in an experimental model of hepatocellular carcinoma …

Emerging role of fascin-1 in the pathogenesis, diagnosis, and treatment of the gastrointestinal cancers

B Ristic, J Kopel, SAA Sherazi, S Gupta, S Sachdeva… - Cancers, 2021 - mdpi.com
Simple Summary Gastrointestinal (GI) cancers, including esophageal, gastric, colorectal,
liver, and pancreatic cancers, remain as one of the leading causes of death worldwide, with …