Specialized receptors that recognize molecular patterns such as double stranded RNA
duplexes—indicative of viral replication—are potent triggers of the innate immune system …

One type of RNA editing converts adenosines to inosines (A→ I editing) in double-stranded
RNA (dsRNA) substrates. A→ I RNA editing is mediated by adenosine deaminase acting on …

Adenosine deaminases acting on RNA (ADARs) catalyze the hydrolytic deamination of
adenosine to inosine in double-stranded RNA (dsRNA) and thereby potentially alter the …

Adenosine deaminase acting on RNA 1 (ADAR1) converts adenosine to inosine in double-
stranded RNA (dsRNA) molecules, a process known as A-to-I editing. ADAR1 deficiency in …

ADAR1 (adenosine deaminase acting on RNA-1) is widely expressed in mammals, but its
biological role is unknown. We show here by gene targeting that ADAR1 selectively edits in …

Sequence-dependent recognition of dsDNA-binding proteins is well understood, yet
sequence-specific recognition of dsRNA by proteins remains largely unknown, despite their …

Backgroud & Aims Gastric cancer (GC) is the third leading cause of global cancer mortality.
Adenosine-to-inosine RNA editing is a recently described novel epigenetic mechanism …

Conspectus The term RNA editing refers to any structural change in an RNA molecule (eg.,
insertion, deletion, or base modification) that changes its coding properties and is not a …

We have conducted a survey of RNA editing in human brain by comparing sequences of
clones from a human brain cDNA library to the reference human genome sequence and to …

Activation-induced cytidine deaminase (AID) is the essential and sole B cell–specific factor
required for class-switch recombination (CSR) and somatic hypermutation (SHM). However …