Type 1 diabetes mellitus (T1D) is a chronic disease characterized by an autoimmune
destruction of insulin-producing β-pancreatic cells. Although many advances have been …

Type 1 diabetes mellitus (T1DM) is the most common chronic autoimmune disease in young
patients and is characterized by the loss of pancreatic β cells; as a result, the body becomes …

Understanding the biology underlying the mechanisms and pathways regulating pancreatic
β cell development is necessary to understand the pathology of diabetes mellitus (DM) …

Simple Summary This review highlights the scope of available treatment options for
neurological diseases, especially stem cell transplantation therapy, which provides new …

Diabetes has been a worldwide healthcare problem for many years. Current methods of
treating diabetes are still largely directed at symptoms, aiming to control the manifestations …

Diabetes mellitus (DM) is one of the most prevalent metabolic disorders. In order to replace
the function of the destroyed pancreatic beta cells in diabetes, islet transplantation is the …

Abstract Background Pancreatic progenitors (PPs) co-expressing the two transcription
factors (TFs) PDX1 and NKX6. 1 are recognized as the indispensable precursors of …

Diabetes mellitus (DM) is a metabolic disease characterized by chronic hyperglycemia as a
result of progressive loss of pancreatic β cells, which could lead to several debilitating …

FOXA2 has been identified as an essential factor for pancreas development and emerging
evidence supports an association between FOXA2 and diabetes. Although the role of …

Recent studies reported that pancreatic β-cells are heterogeneous in terms of their
transcriptional profiles and their abilities for insulin secretion. Sub-populations of pancreatic …