Long-term consequences of traumatic brain injury: current status of potential mechanisms of injury and neurological outcomes

HM Bramlett, WD Dietrich - Journal of neurotrauma, 2015 - liebertpub.com
Traumatic brain injury (TBI) is a significant clinical problem with few therapeutic interventions
successfully translated to the clinic. Increased importance on the progressive, long-term …

Big data from small data: data-sharing in the'long tail'of neuroscience

AR Ferguson, JL Nielson, MH Cragin… - Nature …, 2014 - nature.com
The launch of the US BRAIN and European Human Brain Projects coincides with growing
international efforts toward transparency and increased access to publicly funded research …

Small extracellular vesicles released by infused mesenchymal stromal cells target M2 macrophages and promote TGF‐β upregulation, microvascular stabilization and …

M Nakazaki, T Morita, KL Lankford… - Journal of …, 2021 - Wiley Online Library
Intravenous (IV) infusion of bone marrow‐derived mesenchymal stem/stromal cells (MSCs)
stabilizes the blood‐spinal cord barrier (BSCB) and improves functional recovery in …

Pain and laboratory animals: publication practices for better data reproducibility and better animal welfare

L Carbone, J Austin - PloS one, 2016 - journals.plos.org
Scientists who perform major survival surgery on laboratory animals face a dual welfare and
methodological challenge: how to choose surgical anesthetics and post-operative …

Intravenous infusion of mesenchymal stem cells promotes functional recovery in a model of chronic spinal cord injury

T Morita, M Sasaki, Y Kataoka-Sasaki, M Nakazaki… - Neuroscience, 2016 - Elsevier
Intravenous infusion of mesenchymal stem cells (MSCs) derived from adult bone marrow
improves behavioral function in rat models of spinal cord injury (SCI). However, most studies …

Regulation of the JAK/STAT signaling pathway in spinal cord injury: an updated review

X Guo, C Jiang, Z Chen, X Wang, F Hong… - Frontiers in …, 2023 - frontiersin.org
Cytokines are involved in neural homeostasis and pathological processes associated with
neuroinflammation after spinal cord injury (SCI). The biological effect of cytokines, including …

Diffuse and persistent blood–spinal cord barrier disruption after contusive spinal cord injury rapidly recovers following intravenous infusion of bone marrow …

T Matsushita, KL Lankford, EJ Arroyo, M Sasaki… - Experimental …, 2015 - Elsevier
Intravenous infusion of mesenchymal stem cells (MSCs) has been shown to reduce the
severity of experimental spinal cord injury (SCI), but mechanisms are not fully understood …

Neurotrophic factors for spinal cord repair: Which, where, how and when to apply, and for what period of time?

AR Harvey, SJ Lovett, BT Majda, JH Yoon… - Brain research, 2015 - Elsevier
A variety of neurotrophic factors have been used in attempts to improve morphological and
behavioural outcomes after experimental spinal cord injury (SCI). Here we review many of …

Pre-clinical traumatic brain injury common data elements: toward a common language across laboratories

DH Smith, RR Hicks, VE Johnson… - Journal of …, 2015 - liebertpub.com
Traumatic brain injury (TBI) is a major public health issue exacting a substantial personal
and economic burden globally. With the advent of “big data” approaches to understanding …

[HTML][HTML] Resveratrol, an antioxidant, protects spinal cord injury in rats by suppressing MAPK pathway

S Fu, R Lv, L Wang, H Hou, H Liu, S Shao - Saudi journal of biological …, 2018 - Elsevier
Resveratrol, a polyphenol found in various plants, including grapes, plums and peanuts has
shown various medIRInal properties, including antioxidant, protection of cardiovascular …