Peptide-based supramolecular systems chemistry

F Sheehan, D Sementa, A Jain, M Kumar… - Chemical …, 2021 - ACS Publications
Peptide-based supramolecular systems chemistry seeks to mimic the ability of life forms to
use conserved sets of building blocks and chemical reactions to achieve a bewildering array …

Chemical aspects of human and environmental overload with fluorine

J Han, L Kiss, H Mei, AM Remete… - Chemical …, 2021 - ACS Publications
Over the last 100–120 years, due to the ever-increasing importance of fluorine-containing
compounds in modern technology and daily life, the explosive development of the …

Discovery of small molecule ligands for the von Hippel-Lindau (VHL) E3 ligase and their use as inhibitors and PROTAC degraders

CJ Diehl, A Ciulli - Chemical Society Reviews, 2022 - pubs.rsc.org
The von Hippel-Lindau (VHL) Cullin RING E3 ligase is an essential enzyme in the ubiquitin-
proteasome system that recruits substrates such as the hypoxia inducible factor for …

Collagen and its derivatives: From structure and properties to their applications in food industry

C Tang, K Zhou, Y Zhu, W Zhang, Y Xie, Z Wang… - Food …, 2022 - Elsevier
Collagen is the most abundant extracellular matrix protein in food-producing animals.
Gelatin is partially degraded collagen. Collagen peptides refer to the peptides with specific …

Fluorine and fluorinated motifs in the design and application of bioisosteres for drug design

NA Meanwell - Journal of medicinal chemistry, 2018 - ACS Publications
The electronic properties and relatively small size of fluorine endow it with considerable
versatility as a bioisostere and it has found application as a substitute for lone pairs of …

Processing of collagen based biomaterials and the resulting materials properties

M Meyer - Biomedical engineering online, 2019 - Springer
Collagen, the most abundant extracellular matrix protein in animal kingdom belongs to a
family of fibrous proteins, which transfer load in tissues and which provide a highly …

Applications of fluorine in medicinal chemistry

EP Gillis, KJ Eastman, MD Hill… - Journal of medicinal …, 2015 - ACS Publications
The role of fluorine in drug design and development is expanding rapidly as we learn more
about the unique properties associated with this unusual element and how to deploy it with …

The n→π* Interaction

RW Newberry, RT Raines - Accounts of chemical research, 2017 - ACS Publications
Conspectus The carbonyl group holds a prominent position in chemistry and biology not
only because it allows diverse transformations but also because it supports key …

Collagen‐based biomaterials for wound healing

S Chattopadhyay, RT Raines - Biopolymers, 2014 - Wiley Online Library
With its wide distribution in soft and hard connective tissues, collagen is the most abundant
of animal proteins. In vitro, natural collagen can be formed into highly organized, three …

Collagen structure and stability

MD Shoulders, RT Raines - Annual review of biochemistry, 2009 - annualreviews.org
Collagen is the most abundant protein in animals. This fibrous, structural protein comprises
a right-handed bundle of three parallel, left-handed polyproline II-type helices. Much …