Toward the development of epigenome editing-based therapeutics: potentials and challenges

J Ueda, T Yamazaki, H Funakoshi - International Journal of Molecular …, 2023 - mdpi.com
The advancement in epigenetics research over the past several decades has led to the
potential application of epigenome-editing technologies for the treatment of various …

Saffron, its active components, and their association with DNA and histone modification: A narrative review of current knowledge

M Rashid, H Brim, H Ashktorab - Nutrients, 2022 - mdpi.com
Intensive screening for better and safer medications to treat diseases such as cancer and
inflammatory diseases continue, and some phytochemicals have been discovered to have …

[HTML][HTML] Modelling cell adaptation using internal variables: Accounting for cell plasticity in continuum mathematical biology

M Pérez-Aliacar, J Ayensa-Jiménez… - Computers in Biology and …, 2023 - Elsevier
Cellular adaptation is the ability of cells to change in response to different stimuli and
environmental conditions. It occurs via phenotypic plasticity, that is, changes in gene …

Utilizing Proteomic-Based Strategies to Investigate Molecular Mechanisms of Fragile X Syndrome

D Abbasi - 2024 - search.proquest.com
Fragile X syndrome (FXS) is a neurodevelopment disorder characterized by cognitive
impairment, behavioral challenges, and synaptic abnormalities, with a genetic basis linked …

Comprehensive comparison of transcriptomes in SARS-CoV-2 infection: alternative entry routes and innate immune responses

Y Cao, X Xu, S Kitanovski, L Song, J Wang, P Hao… - bioRxiv, 2021 - biorxiv.org
The pathogenesis of COVID-19 emerges as complex, with multiple factors leading to injury
of different organs. Several studies on underlying cellular processes have produced …

[PDF][PDF] Smad7: a master regulator of β-cell plasticity in T2DM controlled by uric acid

J Joe - 2021 - ourarchive.otago.ac.nz
Abstract Type-2 Diabetes Mellitus (T2DM) is a growing pandemic that affects over 380
million people worldwide, especially in New Zealand where Māori and Pacifica populations …