Antifungal agents in agriculture: friends and foes of public health

VS Brauer, CP Rezende, AM Pessoni, RG De Paula… - Biomolecules, 2019 - mdpi.com
Fungal diseases have been underestimated worldwide but constitute a substantial threat to
several plant and animal species as well as to public health. The increase in the global …

Organocatalysis in aqueous media

MP van Der Helm, B Klemm, R Eelkema - Nature Reviews Chemistry, 2019 - nature.com
Even though enzymes are the cornerstones of living systems, it has so far proven difficult to
deploy artificial catalysts in a biological setting. Organocatalysts are arguably well-suited …

Recent advances in biocatalysis with chemical modification and expanded amino acid alphabet

AD Pagar, MD Patil, DT Flood, TH Yoo… - Chemical …, 2021 - ACS Publications
The two main strategies for enzyme engineering, directed evolution and rational design,
have found widespread applications in improving the intrinsic activities of proteins. Although …

Connected peptide modules enable controlled co-existence of self-assembled fibers inside liquid condensates

A Jain, S Kassem, RS Fisher, B Wang… - Journal of the …, 2022 - ACS Publications
Supramolecular self-assembly of fibrous components and liquid–liquid phase separation
are at the extremes of the order-to-disorder spectrum. They collectively play key roles in …

pH-responsive self-assembly of amyloid fibrils for dual hydrolase-oxidase reactions

M Díaz-Caballero, S Navarro, M Nuez-Martínez… - ACS …, 2020 - ACS Publications
There is an increasing interest in synthetic systems that can execute bioinspired chemical
reactions without requiring the complex structures that characterize enzymes in their …

Biocatalysts based on peptide and peptide conjugate nanostructures

IW Hamley - Biomacromolecules, 2021 - ACS Publications
Peptides and their conjugates (to lipids, bulky N-terminals, or other groups) can self-
assemble into nanostructures such as fibrils, nanotubes, coiled coil bundles, and micelles …

[图书][B] Metal-organic frameworks: Applications in separations and catalysis

H García, S Navalón - 2018 - books.google.com
Focusing on applications in separation, adsorption and catalysis, this handbook underlines
the importance of this hot and exciting topic. It provides an excellent insight into the …

Rational design of hyperstable antibacterial peptides for food preservation

YL Vishweshwaraiah, A Acharya, V Hegde… - npj Science of …, 2021 - nature.com
We describe the design of peptides with properties like thermostability, pH stability, and
antibacterial activity against a few bacterial food pathogens. Insights obtained from classical …

Machine learning identifies chemical characteristics that promote enzyme catalysis

BM Bonk, JW Weis, B Tidor - Journal of the American Chemical …, 2019 - ACS Publications
Despite tremendous progress in understanding and engineering enzymes, knowledge of
how enzyme structures and their dynamics induce observed catalytic properties is …

Copper-containing catalytic amyloids promote phosphoester hydrolysis and tandem reactions

Z Lengyel, CM Rufo, YS Moroz, OV Makhlynets… - ACS …, 2018 - ACS Publications
Self-assembly of short de novo designed peptides gives rise to catalytic amyloids capable of
facilitating multiple chemical transformations. We show that catalytic amyloids can efficiently …