Directed cell migration towards softer environments
How cells sense tissue stiffness to guide cell migration is a fundamental question in
development, fibrosis and cancer. Although durotaxis—cell migration towards increasing …
development, fibrosis and cancer. Although durotaxis—cell migration towards increasing …
Methods of micropatterning and manipulation of cells for biomedical applications
A Martinez-Rivas, GK González-Quijano… - Micromachines, 2017 - mdpi.com
Micropatterning and manipulation of mammalian and bacterial cells are important in
biomedical studies to perform in vitro assays and to evaluate biochemical processes …
biomedical studies to perform in vitro assays and to evaluate biochemical processes …
Anisotropic forces from spatially constrained focal adhesions mediate contact guidance directed cell migration
Directed migration by contact guidance is a poorly understood yet vital phenomenon,
particularly for carcinoma cell invasion on aligned collagen fibres. We demonstrate that for …
particularly for carcinoma cell invasion on aligned collagen fibres. We demonstrate that for …
Microfabricated tissues for investigating traction forces involved in cell migration and tissue morphogenesis
Cell-generated forces drive an array of biological processes ranging from wound healing to
tumor metastasis. Whereas experimental techniques such as traction force microscopy are …
tumor metastasis. Whereas experimental techniques such as traction force microscopy are …
Microtubule-actomyosin mechanical cooperation during contact guidance sensing
ED Tabdanov, V Puram, A Zhovmer, PP Provenzano - Cell reports, 2018 - cell.com
Cancer cell migration through and away from tumors is driven in part by migration along
aligned extracellular matrix, a process known as contact guidance (CG). To concurrently …
aligned extracellular matrix, a process known as contact guidance (CG). To concurrently …
A two-layer skin construct consisting of a collagen hydrogel reinforced by a fibrin-coated polylactide nanofibrous membrane
M Bacakova, J Pajorova, A Broz… - International Journal …, 2019 - Taylor & Francis
Background: Repairs to deep skin wounds continue to be a difficult issue in clinical practice.
A promising approach is to fabricate full-thickness skin substitutes with functions closely …
A promising approach is to fabricate full-thickness skin substitutes with functions closely …
pH modification of high-concentrated collagen bioinks as a factor affecting cell viability, mechanical properties, and printability
J Stepanovska, M Otahal, K Hanzalek, M Supova… - Gels, 2021 - mdpi.com
The 3D bioprinting of cell-incorporated gels is a promising direction in tissue engineering
applications. Collagen-based hydrogels, due to their similarity to extracellular matrix tissue …
applications. Collagen-based hydrogels, due to their similarity to extracellular matrix tissue …
Epithelial tissue geometry directs emergence of bioelectric field and pattern of proliferation
Patterns of proliferation are templated by both gradients of mechanical stress as well as by
gradients in membrane voltage (Vm), which is defined as the electric potential difference …
gradients in membrane voltage (Vm), which is defined as the electric potential difference …
[HTML][HTML] Negative durotaxis: cell movement toward softer environments
How cells sense tissue stiffness to guide cell migration is a fundamental question in
development, fibrosis and cancer. Although durotaxis–traditionally defined as cell migration …
development, fibrosis and cancer. Although durotaxis–traditionally defined as cell migration …
Autoantibodies immuno-mechanically modulate platelet contractile force and bleeding risk
Altered mechanotransduction has been proposed as a putative mechanism for disease
pathophysiology, yet evidence remains scarce. Here we introduce a concept we call single …
pathophysiology, yet evidence remains scarce. Here we introduce a concept we call single …