Depression onset peaks during adolescence and young adulthood. Current treatments are
only moderately effective, driving the search for novel pathophysiological mechanisms …

Major depressive disorders are prevalent conditions with limited treatment response and
remission. Pharmacogenomics tests including CYP2D6 and CYP2C19 genomic variants …

Objective Research on HPA axis dysregulation has been associated with vulnerability to, or
perseverence of, several mental disorders. Hoever, measurements of cortisol levels in …

It is debated as to whether major depressive disorder (MDD) and the burnout syndrome
represent different aspects of the same syndrome or whether they reflect separate entities. A …

Literature supports a causal role of stress in major depressive disorder (MDD). Hair cortisol
concentration (HCC) has been widely used as a measure of long-term stress. Although …

Higher prevalence of depression in females might be associated with sex-specific cortisol
levels. Evidence exists that cortisol levels differ between healthy females and males …

Background The COVID-19 pandemic has put chronic pressure on worldwide healthcare
systems. While the literature regarding the prevalence of psychological distress and …

Background Depressive and anxiety disorders have been linked to a dysregulated
hypothalamus-pituitary-adrenal (HPA)-axis. Hair cortisol levels (HairF) reflect integrated long …

Introduction Burnout symptomatology is associated with various negative health
consequences; however, the mechanisms underlying these associations remain unclear …

Objectives Most of the observed associations of generalized anxiety disorder (GAD), social
anxiety disorder (SAD) and major depressive disorder (MDD) with cortisol concentrations …