LC-MS analysis of chiral amino acids in human urine reveals D-amino acids as potential biomarkers for colorectal cancer

W Deng, C Ye, W Wang, R Huang, C Guo, Y Pan… - … of Chromatography B, 2024 - Elsevier
Colorectal cancer (CRC) is a common malignant tumor in the gastrointestinal tract. Changes
in amino acid metabolites have been implicated in tumorigenesis and disease progression …

Enantioselective transformation of phytoplankton-derived dihydroxypropanesulfonate by marine bacteria

L Liu, X Gao, C Dong, H Wang, X Chen, X Ma… - The ISME …, 2024 - academic.oup.com
Chirality, a fundamental property of matter, is often overlooked in the studies of marine
organic matter cycles. Dihydroxypropanesulfonate (DHPS), a globally abundant …

6-Plex Tandem Phosphorus Tags (TPT) for Accurate Quantitative Proteomics

X Wang, L Ding, Y Zhao, X Gao - Analytical Chemistry, 2024 - ACS Publications
Isobaric chemical labeling is a widely used strategy for high-throughput quantitative
proteomics based on mass spectrometry. However, commercially available reagents have …

A difunctional NMR&CD probe for specific detection and enantiomeric recognition of biothiols in complex mixtures

B Huang, S Lu, F Li - Analytica Chimica Acta, 2024 - Elsevier
Background Biothiols are important for numerous cellular processes, such as resisting
oxidative stress and protecting cell health. Their abnormal levels and molecular …

Stereoselective Amine-omics Using Heavy Atom Isotope Labeled l- and d-Marfey's Reagents

NR Mishra, WG Gutheil - Journal of the American Society for Mass …, 2024 - ACS Publications
Biological amines and amino acids play essential roles in many biochemical processes. The
chemical complexity of biological samples is challenging, and the selective identification …