FLASH radiotherapy and the use of radiation dosimeters

S Siddique, HE Ruda, JCL Chow - Cancers, 2023 - mdpi.com
Simple Summary FLASH radiotherapy (RT) delivering ultra-high dose rate radiation can
reduce normal tissue toxicity while effectively treating tumors. However, implementing …

Evaluation of ion chamber response for applications in electron FLASH radiotherapy

K Liu, S Holmes, B Hooten, E Schüler… - Medical …, 2024 - Wiley Online Library
Ion chambers are required for calibration and reference dosimetry applications in radiation
therapy (RT). However, exposure of ion chambers in ultra‐high dose rate (UHDR) conditions …

Time‐resolved dose rate measurements in pencil beam scanning proton FLASH therapy with a fiber‐coupled scintillator detector system

E Kanouta, PR Poulsen, G Kertzscher… - Medical …, 2023 - Wiley Online Library
Background The spatial and temporal dose rate distribution of pencil beam scanning (PBS)
proton therapy is important in ultra‐high dose rate (UHDR) or FLASH irradiations. Validation …

High‐dose and ultra‐high dose rate (UHDR) evaluation of Al2O3:C optically stimulated luminescent dosimeter nanoDots and powdered LiF:Mg,Ti …

K Liu, B Velasquez, E Schüler - Medical physics, 2024 - Wiley Online Library
Background Dosimetry in ultra‐high dose rate (UHDR) electron beamlines poses a
significant challenge owing to the limited usability of standard dosimeters in high dose and …

Measurement of the bunch structure of a clinical proton beam using a SiPM coupled to a plastic scintillator with an optical fiber

M García Díez, A Espinosa Rodriguez… - Medical …, 2023 - Wiley Online Library
Background Recent proposals of high dose rate plans in protontherapy as well as very short
proton bunches may pose problems to current beam monitor systems. There is an …

[HTML][HTML] Radioluminescence-based fibre optic dosimeters in radiotherapy: a review

I Veronese, CE Andersen, E Li, L Madden… - Radiation …, 2024 - Elsevier
Since their conception in the early 1990s, radioluminescence-based fibre-optic dosimeters
(FODs) have attracted great interest for dosimetric applications in radiotherapy (RT). Over …

Initial experience with an electron FLASH research extension (FLEX) for the Clinac system

K Oh, KJ Gallagher, M Hyun, D Schott… - Journal of applied …, 2024 - Wiley Online Library
Purpose Radiotherapy delivered at ultra‐high‐dose‐rates (≥ 40 Gy/s), that is, FLASH, has
the potential to effectively widen the therapeutic window and considerably improve the care …

A comprehensive investigation of the performance of a commercial scintillator system for applications in electron FLASH radiotherapy

K Liu, S Holmes, E Schüler, S Beddar - Medical physics, 2024 - Wiley Online Library
Background Dosimetry in ultra‐high dose rate (UHDR) beamlines is significantly challenged
by limitations in real‐time monitoring and accurate measurement of beam output, beam …

A small animal irradiation platform for investigating the dependence of the FLASH effect on electron beam parameters

KE Byrne, Y Poirier, J Xu, A Gerry, MJ Foley… - Medical …, 2024 - Wiley Online Library
Background The recent rediscovery of the FLASH effect, a normal tissue sparing
phenomenon observed in ultra‐high dose rate (UHDR) irradiations, has instigated a surge …

Plastic scintillator dosimetry of ultrahigh dose-rate 200 MeV electrons at CLEAR

A Hart, C Giguère, J Bateman, P Korysko… - IEEE Sensors …, 2024 - ieeexplore.ieee.org
Very-high-energy electron (VHEE) beams with energies greater than 100 MeV may be
promising candidates for FLASH radiotherapy due to their favorable dose distributions and …