Genome-wide analyses of introgression between two sympatric Asian oak species
Introgression can be an important source of new alleles for adaption under rapidly changing
environments, perhaps even more important than standing variation. Though introgression …
environments, perhaps even more important than standing variation. Though introgression …
Genomic insights on the contribution of balancing selection and local adaptation to the long‐term survival of a widespread living fossil tree, Cercidiphyllum japonicum
Summary 'Living fossils' are testimonies of long‐term sustained ecological success, but how
demographic history and natural selection contributed to their survival, resilience, and …
demographic history and natural selection contributed to their survival, resilience, and …
ezQTL: a web platform for interactive visualization and colocalization of QTLs and GWAS loci
Genome-wide association studies (GWAS) have identified thousands of genomic loci
associated with complex diseases and traits, including cancer. The vast majority of common …
associated with complex diseases and traits, including cancer. The vast majority of common …
A powerful subset-based method identifies gene set associations and improves interpretation in UK Biobank
Tests of association between a phenotype and a set of genes in a biological pathway can
provide insights into the genetic architecture of complex phenotypes beyond those obtained …
provide insights into the genetic architecture of complex phenotypes beyond those obtained …
[HTML][HTML] Pervasive correlations between causal disease effects of proximal SNPs vary with functional annotations and implicate stabilizing selection
The genetic architecture of human diseases and complex traits has been extensively
studied, but little is known about the relationship of causal disease effect sizes between …
studied, but little is known about the relationship of causal disease effect sizes between …
Alzheimer's Disease Sequencing Project Release 4 Whole Genome Sequencing Dataset
The Alzheimer's Disease Sequencing Project (ADSP) is a national initiative to understand
the genetic architecture of Alzheimer's Disease and Related Dementias (AD/ADRD) by …
the genetic architecture of Alzheimer's Disease and Related Dementias (AD/ADRD) by …
NIAGADS Alzheimer's GenomicsDB: A resource for exploring Alzheimer's disease genetic and genomic knowledge
E Greenfest‐Allen, O Valladares… - Alzheimer's & …, 2024 - Wiley Online Library
Abstract INTRODUCTION The National Institute on Aging Genetics of Alzheimer's Disease
Data Storage Site Alzheimer's Genomics Database (GenomicsDB) is a public knowledge …
Data Storage Site Alzheimer's Genomics Database (GenomicsDB) is a public knowledge …
A powerful subset-based gene-set analysis method identifies novel associations and improves interpretation in UK Biobank
Tests of association between a phenotype and a set of genes in a biological pathway can
provide insights into the genetic architecture of complex phenotypes beyond those obtained …
provide insights into the genetic architecture of complex phenotypes beyond those obtained …
Systematic mediation and interaction analyses in an individual population study help characterize kidney function genetic loci
Chronic kidney disease (CKD) is a complex disease affecting> 10% of the global population,
with large between-and within-continent variability reflecting major environmental effects. To …
with large between-and within-continent variability reflecting major environmental effects. To …
GWLD: an R package for genome-wide linkage disequilibrium analysis
R Zhang, H Wu, Y Li, Z Huang, Z Yin… - G3: Genes …, 2023 - academic.oup.com
Linkage disequilibrium (LD) analysis is fundamental to the investigation of the genetic
architecture of complex traits (eg human disease, animal and plant breeding) and …
architecture of complex traits (eg human disease, animal and plant breeding) and …