Cross-reactive CD4+ T cells enhance SARS-CoV-2 immune responses upon infection and vaccination
INTRODUCTION The clinical manifestations of COVID-19 vary from asymptomatic infection
to respiratory failure. Severe disease courses are primarily associated with advanced age …
to respiratory failure. Severe disease courses are primarily associated with advanced age …
[HTML][HTML] COVID-19 immunobiology: lessons learned, new questions arise
A Kaklamanos, K Belogiannis, P Skendros… - Frontiers in …, 2021 - frontiersin.org
There is strong evidence that COVID-19 pathophysiology is mainly driven by a
spatiotemporal immune deregulation. Both its phenotypic heterogeneity, spanning from …
spatiotemporal immune deregulation. Both its phenotypic heterogeneity, spanning from …
[HTML][HTML] Influenza vaccination reveals sex dimorphic imprints of prior mild COVID-19
R Sparks, WW Lau, C Liu, KL Han, KL Vrindten, G Sun… - Nature, 2023 - nature.com
Acute viral infections can have durable functional impacts on the immune system long after
recovery, but how they affect homeostatic immune states and responses to future …
recovery, but how they affect homeostatic immune states and responses to future …
[HTML][HTML] Cross-reactive immunity against the SARS-CoV-2 Omicron variant is low in pediatric patients with prior COVID-19 or MIS-C
Neutralization capacity of antibodies against Omicron after a prior SARS-CoV-2 infection in
children and adolescents is not well studied. Therefore, we evaluated virus-neutralizing …
children and adolescents is not well studied. Therefore, we evaluated virus-neutralizing …
[HTML][HTML] Antibody affinity and cross-variant neutralization of SARS-CoV-2 Omicron BA. 1, BA. 2 and BA. 3 following third mRNA vaccination
L Bellusci, G Grubbs, FT Zahra, D Forgacs… - Nature …, 2022 - nature.com
There is limited knowledge on durability of neutralization capacity and antibody affinity
maturation generated following two versus three doses of SARS-CoV-2 mRNA vaccines in …
maturation generated following two versus three doses of SARS-CoV-2 mRNA vaccines in …
[HTML][HTML] Stratification of hospitalized COVID-19 patients into clinical severity progression groups by immuno-phenotyping and machine learning
YM Mueller, TJ Schrama, R Ruijten… - Nature …, 2022 - nature.com
Quantitative or qualitative differences in immunity may drive clinical severity in COVID-19.
Although longitudinal studies to record the course of immunological changes are ample …
Although longitudinal studies to record the course of immunological changes are ample …
[HTML][HTML] SARS-CoV-2 immune repertoire in MIS-C and pediatric COVID-19
S Ravichandran, J Tang, G Grubbs, Y Lee… - Nature …, 2021 - nature.com
There is limited understanding of the viral antibody fingerprint following severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children. Herein, SARS-CoV …
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in children. Herein, SARS-CoV …
SARS-CoV-2 serology after COVID-19 in multiple sclerosis: An international cohort study
MP Sormani, I Schiavetti, D Landi… - Multiple Sclerosis …, 2022 - journals.sagepub.com
Background: The MuSC-19 project is an Italian cohort study open to international partners
that collects data on multiple sclerosis (MS) patients with COVID-19. During the second …
that collects data on multiple sclerosis (MS) patients with COVID-19. During the second …
[HTML][HTML] Cross-reactivity of antibodies from non-hospitalized COVID-19 positive individuals against the native, B. 1.351, B. 1.617. 2, and P. 1 SARS-CoV-2 spike …
M Hojjat Jodaylami, A Djaileb, P Ricard, E Lavallee… - Scientific reports, 2021 - nature.com
SARS-CoV-2 variants of concern (VOCs) have emerged worldwide, with implications on the
spread of the pandemic. Characterizing the cross-reactivity of antibodies against these …
spread of the pandemic. Characterizing the cross-reactivity of antibodies against these …