Marine secondary metabolites are a promising source of unexploited drugs that have a wide
structural diversity and have shown a variety of biological activities. These compounds are …

Bacterial biofilms are defined as a surface attached community of bacteria embedded in a
matrix of extracellular polymeric substances that they have produced. When in the biofilm …

Sponges (phylum Porifera) are sessile marine filter feeders that have developed efficient
defense mechanisms against foreign attackers such as viruses, bacteria, or eukaryotic …

Covering: 2006. Previous review: Nat. Prod. Rep., 2007, 24, 31 This review covers the
literature published in 2006 for marine natural products, with 758 citations (534 for the …

Chemical investigation of Indonesian marine sponges Agelas linnaei and A. nakamurai
afforded 24 alkaloid derivatives representing either bromopyrrole or diterpene alkaloids. A …

Tuberculosis has been one of the greatest global health challenges of all time. Although the
current first-line anti-tuberculosis (anti-TB) medicines used in the clinic have reduced …

Antibiotic resistance had first been reported not long after the discovery of the first antibiotic
and has remained a major public health issue ever since. Challenges are constantly …

Despite of the advances made in the treatment and management, tuberculosis (TB) still
remains one of main public health problem. The contrary effects of first and second-line anti …

Covering: 2005. Previous review: Nat. Prod. Rep., 2005, 22, 594 This review covers the
isolation and structures of diterpenoids, including labdanes, clerodanes, pimaranes …

Four new alkaloids,(−)-8′-oxo-agelasine D (2), ageloxime B (3),(+)-2-oxo-agelasidine C
(4), and 4-bromo-N-(butoxymethyl)-1 H-pyrrole-2-carboxamide (5), and the known …