Aim, load, fire: the type VI secretion system, a bacterial nanoweapon

FR Cianfanelli, L Monlezun, SJ Coulthurst - Trends in microbiology, 2016 - cell.com
Bacteria utilise specialised protein secretion systems to interact with host organisms,
competitor bacteria, and the environment. The Type VI secretion system (T6SS) is a versatile …

A view to a kill: the bacterial type VI secretion system

BT Ho, TG Dong, JJ Mekalanos - Cell host & microbe, 2014 - cell.com
The bacterial type VI secretion system (T6SS) is an organelle that is structurally and
mechanistically analogous to an intracellular membrane-attached contractile phage tail …

Protein–protein interactions: co-immunoprecipitation

JS Lin, EM Lai - Bacterial protein secretion systems: Methods and …, 2017 - Springer
Proteins often do not function as single substances but rather as team players in a dynamic
network. Growing evidence shows that protein–protein interactions are crucial in many …

Agrobacterium tumefaciens deploys a superfamily of type VI secretion DNase effectors as weapons for interbacterial competition in planta

LS Ma, A Hachani, JS Lin, A Filloux, EM Lai - Cell host & microbe, 2014 - cell.com
The type VI secretion system (T6SS) is a widespread molecular weapon deployed by many
Proteobacteria to target effectors/toxins into both eukaryotic and prokaryotic cells. We report …

Biogenesis and structure of a type VI secretion membrane core complex

E Durand, VS Nguyen, A Zoued, L Logger… - Nature, 2015 - nature.com
Bacteria share their ecological niches with other microbes. The bacterial type VI secretion
system is one of the key players in microbial competition, as well as being an important …

Structure and regulation of the type VI secretion system

JM Silverman, YR Brunet, E Cascales… - Annual review of …, 2012 - annualreviews.org
The type VI secretion system (T6SS) is a complex and widespread gram-negative bacterial
export pathway with the capacity to translocate protein effectors into a diversity of target cell …

[HTML][HTML] Architecture and assembly of the Type VI secretion system

A Zoued, YR Brunet, E Durand, MS Aschtgen… - … et Biophysica Acta (BBA …, 2014 - Elsevier
The Type VI secretion system (T6SS) delivers protein effectors to diverse cell types including
prokaryotic and eukaryotic cells, therefore it participates in inter-bacterial competition and …

Type VI secretion system: secretion by a contractile nanomachine

M Basler - … Transactions of the Royal Society B …, 2015 - royalsocietypublishing.org
The type VI secretion systems (T6SS) are present in about a quarter of all Gram-negative
bacteria. Several key components of T6SS are evolutionarily related to components of …

Assembly and subcellular localization of bacterial type VI secretion systems

J Wang, M Brodmann, M Basler - Annual review of microbiology, 2019 - annualreviews.org
Bacteria need to deliver large molecules out of the cytosol to the extracellular space or even
across membranes of neighboring cells to influence their environment, prevent predation …

[HTML][HTML] The Type VI secretion system–a widespread and versatile cell targeting system

SJ Coulthurst - Research in microbiology, 2013 - Elsevier
The Type VI secretion system (T6SS) is the most recently described of the Gram-negative
bacterial secretion systems and is widely distributed amongst diverse species. T6SSs are …