Generation of highly productive and mammalian nonpathogenic recombinant H9N2 avian influenza viruses by optimization of 3'end promoter and NS genome

SH An, CY Lee, JG Choi, YJ Lee, JH Kim… - Veterinary microbiology, 2019 - Elsevier
Abstract We developed A/PR/8/34 (PR8) virus-based reverse genetics system in which six
internal genes of PR8 and attenuated hemagglutinin and intact neuraminidase genes of …

Development of highly productive and mammalian non-pathogenic recombinant avian influenza vaccine strains

안세희 - 2020 - s-space.snu.ac.kr
Avian influenza viruses (AIVs) are highly infectious pathogen of waterfowls and can
overcome species barriers to infect mammals by acquiring cumulative mutations. Low …

Novel molecular determinants related with mammalian pathogenicity in influenza A virus

이충용 - 2018 - s-space.snu.ac.kr
Influenza A virus (IAV) is an RNA virus belonging to family Orthomyxoviridae, which contains
negative sense, single-stranded, segmented RNA genomes. IAV is further categorized into …