Titanium alloys in total joint replacement—a materials science perspective
M Long, HJ Rack - Biomaterials, 1998 - Elsevier
Increased use of titanium alloys as biomaterials is occurring due to their lower modulus,
superior biocompatibility and enhanced corrosion resistance when compared to more …
superior biocompatibility and enhanced corrosion resistance when compared to more …
Calcium phosphate coatings on magnesium alloys for biomedical applications: a review
S Shadanbaz, GJ Dias - Acta biomaterialia, 2012 - Elsevier
Magnesium has been suggested as a revolutionary biodegradable metal for use as an
orthopaedic material. As a biocompatible and degradable metal, it has several advantages …
orthopaedic material. As a biocompatible and degradable metal, it has several advantages …
Dissemination of wear particles to the liver, spleen, and abdominal lymph nodes of patients with hip or knee replacement
Background: The importance of particles generated by wear and corrosion of joint
replacement prostheses has been understood primarily in the context of the local effects of …
replacement prostheses has been understood primarily in the context of the local effects of …
History and systematic review of wear and osteolysis outcomes for first-generation highly crosslinked polyethylene
SM Kurtz, HA Gawel, JD Patel - Clinical Orthopaedics and …, 2011 - journals.lww.com
Background Highly crosslinked polyethylene (HXLPE) was introduced to reduce wear and
osteolysis in total joint arthroplasty. While many studies report wear and osteolysis …
osteolysis in total joint arthroplasty. While many studies report wear and osteolysis …
The molecular triad OPG/RANK/RANKL: involvement in the orchestration of pathophysiological bone remodeling
S Theoleyre, Y Wittrant, SK Tat, Y Fortun… - Cytokine & growth factor …, 2004 - Elsevier
The past decade has seen an explosion in the field of bone biology. The area of bone
biology over this period of time has been marked by a number of key discoveries that have …
biology over this period of time has been marked by a number of key discoveries that have …
Biologic effects of implant debris.
Biologic response to orthopedic implants debris is central to clinical performance. Eventual
implant loosening due to aseptic osteolysis has been attributed to local inflammatory …
implant loosening due to aseptic osteolysis has been attributed to local inflammatory …
Metal release in patients who have had a primary total hip arthroplasty. A prospective, controlled, longitudinal study
There is an increasing recognition that, in the long term, total joint replacement may be
associated with adverse local and remote tissue responses that are mediated by the …
associated with adverse local and remote tissue responses that are mediated by the …
Osteoarthritis: new insights. Part 2: treatment approaches
DT Felson, RC Lawrence, MC Hochberg… - Annals of internal …, 2000 - acpjournals.org
Osteoarthritis is the most common form of arthritis, affecting millions of people in the United
States. It is a complex disease whose etiology bridges biomechanics and biochemistry …
States. It is a complex disease whose etiology bridges biomechanics and biochemistry …
Total knee replacement in young, active patients. Long-term follow-up and functional outcome
DR Diduch, JN Insall, WN Scott, GR Scuderi… - Jbjs, 1997 - journals.lww.com
We reviewed our experience with total knee arthroplasties performed between 1977 and
1992 in patients who were fifty-five years old or less to determine the appropriate …
1992 in patients who were fifty-five years old or less to determine the appropriate …
Osteoblast proliferation and maturation by bisphosphonates
GI Im, SA Qureshi, J Kenney, HE Rubash… - Biomaterials, 2004 - Elsevier
Aseptic loosening and osteolysis are currently the most common causes of failure of total
joint replacements. Osteolysis is initiated by a macrophage response to wear debris …
joint replacements. Osteolysis is initiated by a macrophage response to wear debris …